Ronald palacios castrillo2026-03-222026-03-22202310.20944/preprints202312.0132.v1https://doi.org/10.20944/preprints202312.0132.v1https://andeanlibrary.org/handle/123456789/84244Among the number of hurdles that the vaccines based in modRNA platforms have been facing, there is now another critical one: immune imprinting which decreases even more the effectiveness of the modRNA Covid vaccines.enImprinting (psychology)Coronavirus disease 2019 (COVID-19)Immune system2019-20 coronavirus outbreakSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)BiologyVirologyImmunologyUnraveling the Tapestry: Immune Imprinting Amidst a Spectrum of Challenges for modRNA COVID-19 Vaccinespreprint