Willy RamosAlfredo Enrique Oyola-GarcíaAida AguirreJhony A. De La Cruz‐VargasMiguel LunaTania AlarcónMónica MeléndezJuan Huaccho-RojasYudy Condor-Rojas2026-03-222026-03-22202410.1101/2024.03.18.24304491https://doi.org/10.1101/2024.03.18.24304491https://andeanlibrary.org/handle/123456789/84277ABSTRACT OBJECTIVE To perform a dengue-related death time analysis that occurred in Piura and Ica (Peru) during the atmospheric phenomena of El Niño Costero and Cyclone Yaku in 2023. MATERIAL AND METHODS A case-series study was performed. We included the deaths between January 1 and June 3, 2023. We reviewed the research data base of the deaths as well as the clinical epidemiology records, death certificates and laboratory test results. A time analysis was performed from the date of onset of symptoms, date of first visit at a health establishment, date that dengue diagnosis was first registered and date of death. RESULTS We included 40 deaths by dengue in the study. 70% were females, the median age of death was 51 years of age, and 70% came from Piura. 51.2% presented some comorbidity and 14% had self-medicated with metamizole, other NSAIDS or corticoids before the initial medical consultation. 37.5% presented an unconventional clinical pattern at admission and dengue was not suspected in 40% during the initial assessment. The median time until the initial assessment, the diagnosis time, and the time from diagnosis until death were 3 days, 0 days, and 1 day, respectively. Adults presented a time until the initial assessment significantly greater than the other age groups (p=0.048), the diagnosis time was significantly less than those seen at the Health Department establishments and regional government establishments (MINSA/GORE) than in private establishments (p=0.014) and greater in pediatrics (p=0.018). The time from diagnosis until death was significantly less in those that self-medicated before the initial assessment (p=0.041). CONCLUSION The adults presented a significantly greater time until the initial assessment; the diagnosis time was less than those seen in MINSA/GORE establishments and greater in pediatrics, furthermore, the time from diagnosis until death was significantly less in those who self-medicated before the initial assessment. An important fraction of deaths presented comorbidities and an unconventional clinical pattern at admission, with dengue frequently not suspected during the initial assessment.enDengue feverMedicineEpidemiologyPediatricsMedical recordDemographyEmergency medicinepreprint