Gonzalo MoratorioMariela MartínezMaría Fernanda GutiérrezKatiuska GonzálezRodney ColinaLuis Fernando López TortLilia LópezRicardo RecareyAlejandro G. SchijmanPilar Moreno2026-03-222026-03-22200710.1186/1743-422x-4-79https://doi.org/10.1186/1743-422x-4-79https://andeanlibrary.org/handle/123456789/50019Citaciones: 10Phylogentic analysis revealed the presence of a sequence signature in the 5'NCR of type 1 HCV strains isolated in South America. This signature is frequent enough in type 1 HCV populations circulating South America to be detected in a phylogenetic tree analysis as a distinct type 1 sub-population. The coexistence of distinct type 1 HCV subpopulations is consistent with quasispecies dynamics, and suggests that multiple coexisting subpopulations may allow the virus to adapt to its human host populations.enPhylogenetic treeBiologyLineage (genetic)Hepatitis C virusVirologyPhylogeneticsGeneticsCoding regionEvolutionary biologyGenotypearticle