Esteban Moreno-MonteroRodrigo Moreta‐HerreraJosé A. RodasEvelyn Cuesta-AndaluzDiana Ximena Puerta-CortésDaniela Ferrufino-BorjaDaniel OleasRenzo Gismondi Diaz2026-03-222026-03-22202510.1371/journal.pone.0331042https://doi.org/10.1371/journal.pone.0331042https://andeanlibrary.org/handle/123456789/77819Anxiety were associated with cognitive processes related to meaning-making and hope, supporting their role as protective psychological variables. However, cultural context modulates the strength of these relationships, highlighting the need for context-sensitive interventions.enContext (archaeology)PsychologyAnxietyCognitionPurpose in lifeClinical psychologyDevelopmental psychologyThe mediating role of hope in the relationship between purpose in life and anxiety: A cross-cultural analysis in university studentsarticle