José Liders Burgos ZuletaRoger Carillo MezoEduardo Perusquia OrtegaBeatriz Luna BarrónRubén Conde EspinosaDiana P Marín MuentesJulián Sánchez CortázarM.F. CátedraJosé Álvaro Burgos ZuletaJosé Andres Burgos Zuleta2026-03-222026-03-22201610.3332/ecancer.2014.436https://doi.org/10.3332/ecancer.2014.436https://andeanlibrary.org/handle/123456789/87043Citaciones: 1Gelastic seizure was first described by Trousseau in 1877 and comes from the Greek word gelos (laughs), as laughter is the main feature [1]. Normal laughter is a reactive emotional behaviour and motor action that involves the limbic system, hypothalamus, temporal cortex, and several regions of the brainstem. A female patient, six years old, left-handed, with gelastic seizures, uncontrolled despite being treated with two antiepileptic drugs at high doses, was treated. A simple axial tomography was done, where a hypodense lesion that shapes the inner table of the skull temporal level was observed; later, magnetic resonance imaging was requested, better characterising an intraxial lesion in the right second temporal gyrus cystic appearance.enGelastic seizureHypothalamic hamartomaMedicineBrainstemLesionLaughterMagnetic resonance imagingNeuroscienceGyrusparatext