José A. BravoJosé VilaJ. Mauricio PeñarrietaPatricia Mollinedo2026-03-222026-03-22201510.13140/rg.2.1.5142.7044https://doi.org/10.13140/rg.2.1.5142.7044https://andeanlibrary.org/handle/123456789/85898"This is a short review on some available information regarding recent advances in the application of new approaches to the establishment of the close relationship conformation/configuration in flexible systems. These are usually characterized by containing a number of stereogenic sites and it became interesting to evaluate how the new tools could help in defining configurations. The new developments are particularly suitable for the analysis of natural products. Indeed, we are here circumscribed only to the so-called “J-based approach”."enStereocenterNatural (archaeology)Computer scienceBiochemical engineeringChemistryreview