Elsa NievesMireya SánchezMaritza Rondón2026-03-222026-03-222013http://dialnet.unirioja.es/servlet/oaiart?codigo=4232296https://andeanlibrary.org/handle/123456789/63003The sandflies are haematophagous insects transmitting Leishmania, the causative agent of leishmaniasis, a disease that has a broad clinical spectrum in humans. This paper is a review on the saliva of sandflies in the transmission of Leishmania and the epidemiological impact. It first addresses the potential of the saliva of sandflies as a drug cocktail that is involved in the insect's biology, in the process of infection with Leishmania, their ability to be used as an epidemiological marker and protein source for a vaccine against leishmaniasisesLeishmaniaLeishmaniasisVirologyEpidemiologyBiologyLeishmania majorMedicineImmunologyarticle