L. Rizo TopetePaola Borbolla-FloresC. CortézE. Pérez-AlbaJ.F. Moreno De HoyosLeonardo Rodríguez-ReyesRolando Claure-Del Granado2026-03-222026-03-22202310.1016/j.ekir.2023.02.028https://doi.org/10.1016/j.ekir.2023.02.028https://andeanlibrary.org/handle/123456789/58457Citaciones: 1Hemophagocytic lymphohistiocytosis (HLH) is an aggressive and life-threatening syndrome of excessive immune activation, it characterizes by abnormal activation of macrophages and T cells that causes cytokine storm, with high morbidity and mortality. HLH is associated with autoimmune diseases, infections, malignancy, immunosuppression, human immunodeficiency virus (HIV). HLH has a high risk of progression to multi-organ disfunction syndrome (MODS) including acute kidney injury (AKI).HLH usually presents as an acute or subacute febrile illness associated with multiple organ involvement.enMedicineHemophagocytic lymphohistiocytosisMacrophage activation syndromeCytokine stormImmunosuppressionImmunologyAcute kidney injuryMalignancyMultiple organ dysfunction syndromeSepsisarticle