Mitochondrial Disorders After 12 Months of Human Immunodeficiency Virus Type 1 Preexposure Prophylaxis Based on Tenofovir Disoproxil Fumarate Plus Emtricitabine in Healthy Adults

Esperanza Muñoz‐MuelaMarta Mejías-TruebaAna Serna‐GallegoAbraham Saborido-AlconchelSusana Fernández-PérezMarta HerreroCésar SotomayorAlicia Gutiérrez‐ValenciaMaría Trujillo‐RodríguezLuís F. López‐Cortés2026-03-222026-03-22202510.1093/infdis/jiaf156https://doi.org/10.1093/infdis/jiaf156https://andeanlibrary.org/handle/123456789/44037Citaciones: 4TDF/FTC-based PrEP induces mitochondrial toxicity in healthy subjects after 12 months of treatment, negatively affecting mitochondrial function and morphology.enEmtricitabineTenofovirPre-exposure prophylaxisHuman immunodeficiency virus (HIV)MedicineVirologyMitochondrial Disorders After 12 Months of Human Immunodeficiency Virus Type 1 Preexposure Prophylaxis Based on Tenofovir Disoproxil Fumarate Plus Emtricitabine in Healthy Adultsarticle