Samane Memar MasjedBatool AkhlaghiniaMonireh ZarghaniNasrin Razavi2026-03-222026-03-22201610.1071/ch16126https://doi.org/10.1071/ch16126https://andeanlibrary.org/handle/123456789/45485Citaciones: 21We describe an efficient method for the direct preparation of nitriles from aldehydes and hydroxylamine hydrochloride catalyzed by sulfonated nanohydroxyapatite functionalized by 2-aminoethyl dihydrogen phosphate (HAP@AEPH2-SO3H) as an eco-friendly and recyclable solid acid nanocatalyst. In this protocol the use of a solid acid nanocatalyst provides a green, useful, and rapid method for the preparation of nitriles in excellent yields. In addition, the notable feature of this methodolgy is that the synthesized nanocatalyst can be recovered and reused five times without any noticeable loss of efficiency.enHydroxylamine HydrochlorideChemistryGreen chemistryCatalysisHydroxylamineBiocatalysisSolid acidIonic liquidHydrochlorideOrganic chemistryarticle