Improved Completion Rates and Characterization of Drug Reactions with an Intensive Chagas Disease Treatment Program in Rural Bolivia

Jeffrey A. TornheimDaniel Franz Lozano BeltránRobert H. GilmanMario CastellonMarco SolanoWalter SullcaFaustino TorricoCaryn Bern2026-03-222026-03-22201310.1371/journal.pntd.0002407https://doi.org/10.1371/journal.pntd.0002407https://andeanlibrary.org/handle/123456789/45312Citaciones: 26Intensive management improved completion and identified more ADEs, but did not reduce moderate or severe ADEs. Risk of dermatologic ADEs cannot be reduced by selecting younger adults or monitoring only during the first few weeks of treatment. Pill counts and phone-based encounters are reliable tools for treatment programming in rural Bolivia.enMedicineBenznidazoleProspective cohort studyPillAdverse effectInternal medicinePediatricsImproved Completion Rates and Characterization of Drug Reactions with an Intensive Chagas Disease Treatment Program in Rural Boliviaarticle