Miguel Guzmán-Rivero2026-03-222026-03-22202310.32388/72jzowhttps://doi.org/10.32388/72jzowhttps://andeanlibrary.org/handle/123456789/86988Potential competing interests: No potential competing interests to declare.I highlight my previous comments.It is a work that provides an explanatory analysis regarding the Evolution of new variants of SARS-CoV-2during the pandemic.I consider it to be a great contribution in this sense that allows us to understand the presence of different variants of SARS-CoV-2 in a fairly short period of time.which also serves to evaluate the usefulness of the vaccines developed against this virus.enSelection (genetic algorithm)PandemicBiologyMutationCoronavirus disease 2019 (COVID-19)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)GeneticsVirologyComputational biologyEvolutionary biologypeer-review