Jorge H UlloaDavid J SabbagJavier del CastilloAlexa RuedaVictoria T. LeeLishan AklogBrian J. deGuzman2026-03-222026-03-22202610.1177/11297298261415957https://doi.org/10.1177/11297298261415957https://andeanlibrary.org/handle/123456789/79604This novel, fully subcutaneous IO device appears to be a feasible, usable, and safe option for short-term infusion therapy in patients with CKD or challenging venous access. These findings support further investigation into its use as a long-term intraosseous vascular access option.enMedicineVascular accessSurgeryVenous accessAnesthesiaVascular closure deviceFirst-in-human evaluation of a novel subcutaneous intraosseous vascular access device for outpatient infusionsarticle