Roberto Rendón MedelStella M. DieguezM. BrindoSullivan A. AyusoC.A. CánepaADOLFO RUARTEMiguel Luis Podestá2026-03-222026-03-22199810.1046/j.1464-410x.1998.00007.xhttps://doi.org/10.1046/j.1464-410x.1998.00007.xhttps://andeanlibrary.org/handle/123456789/48115Citaciones: 47Polyuria occurred in all patients with MPE, independently of the response to desmopressin. Responders had the lowest AVP values over the 24 h; the morning AVP levels differentiated normal subjects from enuretic patients and responders from non-responders. In patients with MPE, clinically undetected bladder instability was unrelated to the results of treatment and there were no urodynamic changes during desmopressin treatment. The differences between enuretic patients suggested a different aetiology of MPE, probably related to an increase in PGE2 concentration and an antagonistic mechanism of action of AVP or desmopressin.enMedicineDesmopressinEnuresisHumanitiesPediatricsarticle