Danyang DaiPedro Henrique França GoisMarina WainsteinMoji GhadimiNicholas SpyrisonRolando Claure‐Del GranadoSally ShrapnelJason D. PoleISARIC Characterization Group2026-03-222026-03-22202510.1371/journal.pone.0336843https://doi.org/10.1371/journal.pone.0336843https://andeanlibrary.org/handle/123456789/78426After adjusting for demographics, comorbidities, laboratory findings, and treatments, patients in ICU during the Omicron wave were less likely to develop AKI compared to previous eras. Nevertheless, the precise influence of the Omicron variant on kidney function remains a subject of ongoing discussion.enAcute kidney injuryMedicineEmergency medicineIntensive care medicineKidney diseaseIntensive care unitRenal functionKidneyInternal medicineSurgeOmicron surge impact on acute kidney injury in ICU patients: A study using the ISARIC COVID-19 databasearticle