Direct evidence gap on fixed versus adjusted‐dose benznidazole for adults with chronic Chagas disease without cardiomyopathy: Systematic review and individual patient data meta‐analysis

Agustín CiapponiFabiana BarreiraLucas PerelliAriel BardachJoaquím GascónIsrael MolinaCarlos A. MorilloNilda Graciela PradoAdelina RiarteFaustino Torrico2026-03-222026-03-22202210.1111/tmi.13831https://doi.org/10.1111/tmi.13831https://andeanlibrary.org/handle/123456789/85798Citaciones: 10The study protocol was registered in PROSPERO (CRD42019120905).enMedicineBenznidazoleMeta-analysisOdds ratioPlaceboInternal medicineMEDLINESubgroup analysisRandomized controlled trialConfidence intervalDirect evidence gap on fixed versus adjusted‐dose benznidazole for adults with chronic Chagas disease without cardiomyopathy: Systematic review and individual patient data meta‐analysisreview