Browsing by Autor "Dionicia Zeballos"

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    WCN24-2644 VITAMIN B COMPLEX IN LIVING KIDNEY DONORS
    (Elsevier BV, 2024) I.S.R.A.E.L. RIVAS; M.A.B.E.L. MERIDA; Dionicia Zeballos; Carlos Agustín León Román
    The practice of kidney transplantation enhances the quality of life and improves the rates of survivance in patients with chronical renal diseases. In the case of a kidney transplant with a living donor, different mechanisms are being sought to improve residual renal function. Preclinical studies have identified the upregulation of NAD+ as a potential strategy for the prevention and treatment of AKI (acute kidney injury). NAD+ is the final metabolized form of vitamin B3. A recent clinical study found that COVID-19-related AKI was associated with NAD+ biosynthetic impairment arising in the context of ischemic, inflammatory, or toxic kidney injury.