Browsing by Autor "Henrry Temis Quisbert Vasquez"

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Choledochal cyst in a pediatric patient with Down syndrome, a diagnostic challenge
(2024) Henrry Temis Quisbert Vasquez; Jhossmar Cristians Auza-Santiváñez; Gabriela Moscoso Zurita; Liliana Heydi Suarez Laime; Blas Apaza-Huanca; Giovanni Callizaya Macedo
Introduction. Down syndrome (DS) is the most common chromosomal alteration. Mortality during the first year of life in this group is high. Newborns with this condition have a higher risk of developing cholestasis. Infants with DS can develop cysts. of common bile duct secondary to cholestasis, in pediatric patients common bile duct cysts are a rare pathology. Clinical Case. 9-month-old infant with a history of DS. On general physical examination, the skin and mucous membranes were generally moist and jaundiced, isochoric and photoreactive pupils, icteric sclerae, with hepatomegaly 3 cm below the costal margin and splenomegaly 2 cm from the rib cage, abdominal perimeter 49 cm. Laboratory and imaging studies, including cholangioresonance, are performed to confirm the diagnosis of Todani IVa choledochal cyst.Conclusions. In patients with Down syndrome who present a clinical picture of vomiting, abdominal pain and jaundice, the diagnosis of choledochal cyst should be considered. Cholangioresonance is the study that confirms the presence of a choledochal cyst. Our clinical case was evaluated by the surgery service and a surgical procedure was scheduled for resection of the cyst
Impact of Altitude on Cardiovascular Physiology: Literature Review and Update
(2025) Jhossmar Cristians Auza-Santiváñez; Henrry Temis Quisbert Vasquez; Freddy Ednildon Bautista-Vanegas; Delly Espejo-Alanoca; Ponciano Chiri-Chambi; Victor Hugo Mamani Huarachi; Benito Aguirre-Cruz; Katrin Daniela Sivila-Marquez; Jose Luis Diaz-Guerrero
Introduction: More than 140 million people in the world live at high altitudes, above 2,500 meters (m) above sea level. Oxygen is vital for cellular metabolism; therefore, hypoxic conditions found at high altitude affect all physiological functions. Metods: A search for information was carried out in the SciELO, Scopus, PubMed/MedLine databases, the Google Scholar search engine, as well as in the ClinicalKeys services. Advanced search strategies were used to retrieve the information, by structuring search formulas using the terms "Cardiovascular Physiology", "Cardiovascular Physiology at Altitude", as well as their translations into Spanish " Fisiología Cardiovascular " and " Fisiología Cardiovascular en la altitud ". Results discussion: The heart is composed of three main types of cardiac muscle: atrial muscle, ventricular muscle, and specialized excitatory and conductive muscle fibers. The efficiency and work of the heart as a pump is often measured in terms of cardiac output, or the amount of blood the heart pumps per minute. Cardiac output is the product of stroke volume and heart rate Cardiovascular Changes at Altitude It is possible to think of the goal of acclimatization as maintaining oxygen delivery to the tissues as close to normal as possible. The cardiovascular system is central to this. Acute exposure to high altitude produces an increase in heart rate and cardiac output both at rest and for a given amount of work compared with sea level. In general, the normal heart tolerates even severe hypoxia very well. The heart, as a hemodynamic pump, has two mechanisms at its disposal to enhance its performance: heart rate and stroke volume, which together constitute cardiac output. The altitude electrocardiogram shows a variably increased amplitude of the P wave, deviation of the QRS axis to the right, and signs of right ventricular overload and hypertrophy. Conclusions: Advances in high-altitude research have shown that the cardiovascular system deploys some efficient mechanisms of acclimatization to oxygen deprivation, and the healthy heart adapts to hypoxia, even when severe, with preservation of systolic function and only minor impairment of LV and RV diastolic function. With acclimatization, desensitization of the adrenergic system, together with increased parasympathetic influence, leads to a decrease in maximum heart rate and protection of the myocardium against potentially damaging energy imbalances. Acute exposure to high altitude stimulates the adrenergic system, increasing heart rate and cardiac output; although arterial pressure remains stable, pulmonary artery pressure increases due to hypoxic pulmonary vasoconstriction. Our improved understanding of the effect of altitude hypoxia on the cardiovascular system will allow better-informed, evidence-based advice for patients with pre-existing cardiovascular disease
Overweight, Obesity and High Blood Pressure: Early Atherogenic Signs in Children Aged 3 to 7 Years
(2025) Jhossmar Cristians Auza-Santiváñez; Freddy Ednildon Bautista-Vanegas; Ingrid Neysa Cabezas-Soliz; Henrry Temis Quisbert Vasquez; Yenifer Zelaya-Espinoza; Jorge Márquez-Molina; Delly Espejo-Alanoca; Paola Kattya Barrientos Lujan; Isaura Oberson Santander
Introduction: Human atherosclerosis has been considered for centuries as one of the greatest predators of health, its distribution on the planet is so wide that it overwhelmingly surpasses any other pathological process and reaches epidemic proportions, both in economically developed populations and in the process of becoming so.Objective: To identify the presence of overweight, obesity and arterial hypertension as early signs of atherosclerosis in children aged 3-7 years.Methods: A descriptive-analytical cross-sectional epidemiological study was carried out in 5 clinics of the "19 de abril" University Polyclinic, in the Plaza de la Revolución municipality, Havana City, during the period 2022-2023. The sample consisted of 152 children aged 3 to 7 years who met the inclusion criteria. The data were collected using the new model (AtecomR) and stored in an automated database in Microsoft Access. Statistical processing was performed using the SPSS statistical package, through a Toshiba Intel (R) Pentium IV microprocessor.Conclusion: This study constitutes a preamble for other investigations that address the problem of cardiovascular disease from the perspective of intrauterine life. The results have provided certain evidence, which, together with a review of the literature, has allowed us to propose the following conclusions. A high frequency of obesity, overweight and high blood pressure levels was identified in the study population. It was observed that in the obese and overweight group they had a tendency to increase with age, being higher their frequency between five and six years respectively. It was shown that overweight and obesity in children were factors for the presence of alterations in blood pressure.
Ramsay Hunt Syndrome in a Pediatric Patient with Atypical Presentation: Case Report
(2025) C. Roman; Paola Nielsen Fuentes Luzcuber; Jhossmar Cristians Auza-Santiváñez; Carmen Julia Salvatierra Rocha; Edson Grover Sañez Liendo; Henrry Temis Quisbert Vasquez; Mildred Ericka Kubatz La Madrid; Benito Aguirre-Cruz; Delly Espejo-Alanoca
The case of a preschooler with Ramsay Hunt Syndrome (RHS) is reported, an infrequent pediatric neurological condition caused by the reactivation of the varicella-zoster virus, whose atypical manifestation represented a diagnostic challenge. The patient, a 3-year and 4-month-old male, presented with vesicular lesions on the forehead and periorbital region, without the classic auricular rash, which led to a delayed diagnosis. Once RHS with bacterial superinfection was confirmed, acyclovir, prednisone, and antibiotics were administered, achieving a favorable evolution. The atypical presentation highlights the diagnostic challenges in children and the risk of delayed management. Therefore, it is crucial to maintain a high index of suspicion for RHS in pediatrics, even with unusual presentations, to ensure early treatment and prevent severe long-term complications.
Unraveling ADHD: Evidence, controversies, and new therapeutic opportunities
(2025) Fidel Aguilar-Medrano; Freddy Ednildon Bautista-Vanegas; Isis Scarleth Funes Galindo; Carmen Julia Salvatierra Rocha; Henrry Temis Quisbert Vasquez; Reyna Georgina Gonzales; Ingrid Neysa Cabezas-Soliz; Delly Espejo-Alanoca; Jhossmar Cristians Auza-Santiváñez
Introduction. ADHD is one of the most common neurodevelopmental disorders, affecting millions of children and adults worldwide. The significance of ADHD extends far beyond its prevalence. It impacts multiple areas of life, including academic achievement, job performance, relationships, and mental health. Significant challenges remain in terms of diagnosis and treatment. Methods. A search for information was conducted from January to June 2025 in the databases SciELO, Scopus, PubMed/MedLine, Google Scholar, Cochrane Library, as well as Clinical Keys services. From the resulting documents, those written in the last 10 years were selected; this time range was prioritized; some systematic reviews covered broader periods, such as the last 5 years, the last 10 years, or even did not apply a specific date limit. Conclusions. Attention-Deficit Hyperactivity Disorder (ADHD) represents a multifactorial challenge that transcends the clinical context to involve neurobiological, psychosocial, and cultural dimensions. Empowering patients and their families through psychoeducation strengthens understanding of the disorder, especially in vulnerable populations such as children, adolescents, and young adults. Investing in research, therapeutic innovation, and equitable public policies will be key to transforming ADHD care into a real opportunity to improve the quality of life for those who suffer from it.