Browsing by Autor "Manuel Justiniano"

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    Prevalencia y tipos de glaucoma en Bolivia
    (2024) Manuel Justiniano; Rolando Olguín; Denisse Aliaga; R. Q.; Lucía Villarroel
    Objetivo: Describir la frecuencia y distribución de los diferentes tipos de glaucoma que afectan a la población boliviana. Métodos: Estudio epidemiológico y retrospectivo que incluyó a los pacientes con glaucoma atendidos en 5 centros de las 3 ciudades principales de Bolivia (La Paz, Cochabamba y Santa Cruz) durante un período de 9 meses (enero a septiembre de 2019). Se incluyeron a todos los pacientes con diagnóstico de glaucoma registrando los datos de edad, género y tipo de glaucoma. Los resultados se analizaron para determinar la prevalencia de los diferentes tipos de glaucoma y su asociación a género, edad y distribución geográfica. Resultados: Se detectaron 884 pacientes con glaucoma: 478 con diagnóstico de ángulo abierto (53,88%); 216 con ángulo estrecho u ocluible (24,35%); 150 con diagnóstico de ángulo cerrado (16,91%) y 40 pacientes con otros tipos de glaucoma (congénito, traumático, uveítico, etc.) (4,84%). Del total de casos, 118 (13,3%) presentaban pseudoexfoliación capsular. En todos los tipos de glaucoma predominó el sexo femenino, con un total de 589 casos (66,6%) contra 295 (33,4%) casos masculinos. Conclusiones: En Bolivia la relación entre glaucomas de ángulo abierto versus cerrado ha sido de 1,3, similar a las estadísticas de países asiáticos. Esto marca un cambio en la forma en que los oftalmólogos bolivianos deberían detectar y tratar el glaucoma, dando especial atención a la gonioscopía y síntomas subagudos de crisis de cierre angular.
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    Surgical procedures in glaucoma: A preferred practice pattern report by the Latin American Glaucoma Society.
    (National Institutes of Health, 2026) Manuel Justiniano; Juan José Mura; Jair Giampani; Marcelo Jordão Lopes Silva; Guillermo Barreto Fong
    Among specialists of the Latin American Glaucoma Society, trabeculectomy and glaucoma drainage devices remain the most commonly performed surgical procedures. Minimally invasive glaucoma surgery is primarily used in combination with cataract surgery, while ciliary body laser procedures are generally reserved for cases of previous glaucoma drainage device failure or as an initial option for newly diagnosed glaucoma cases.
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    Triple-fixed Combination of Dorzolamide/Timolol/Brimonidine: Efficacy Study in Bolivian Population
    (2025) Manuel Justiniano; Giselle Rodríguez; María Silvia Passerini
    Justiniano JM, Rodríguez GM, Passerini MS. Triple-fixed Combination of Dorzolamide/Timolol/Brimonidine: Efficacy Study in Bolivian Population. J Curr Glaucoma Pract 2024;18(4):137-141.
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    Twelve-month outcomes of Kahook dual blade goniotomy combined with cataract surgery in Latino patients
    (Springer Science+Business Media, 2024) Gustavo Espinoza; Manuel Justiniano; Ignácio Rodriguez-Uña; Fernando Godín; Andrés Arango; Sylvia J. Villamizar
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    Twelve-month outcomes of Kahook Dual Blade goniotomy combined with cataract surgery in Latino patients
    (Research Square (United States), 2022) Gustavo Espinoza; Manuel Justiniano; Ignácio Rodriguez-Uña; Fernando Godín; Andrés Arango; Sylvia J. Villamizar
    Abstract Purpose: To evaluate 12-month surgical outcome of Kahook Dual Blade (KDB) goniotomy in combination with cataract surgery in Latino patients with open angle glaucoma (OAG) and ocular hypertension (OHT). Methods: This retrospective study included 45 eyes of 40 patients who underwent KDB goniotomy combined with cataract extraction from January 2016 to September 2020 at two centers in South America. Primary outcome was surgical success was defined as ≥20% intraocular pressure (IOP) reduction or ≥1 medication reduction from preoperative without additional IOP-lowering procedures and an IOP ≥5 mmHg or ≤21 mmHg. Additionally, we used 2 cutoffs values for success of IOP ≤18 and ≤15 mmHg. Secondary outcomes included: IOP, medication use, best corrected visual acuity, complications and failure-associated factors. Results: Success rates at 12 months with cutoff limits of 21, 18 and 15 mmHg were 84.3%, 75.6% and 58.7%, respectively. At 12 months, mean preoperative IOP significantly decreased from 19.23 ± 0.65 mmHg on 2.33 ± 1.04 medications to 14.33 ± 0.66 mmHg on 0.59 ± 0.94 medications, with 62% of eyes free of hypotensive medication. Eyes that developed postoperative IOP spikes had higher risk for failure using the cutoff limit of IOP ≤18 mmHg with a hazard ratio of 3.6 (95% confidence interval [CI], 1.80-7.13; p<0.001). There were no serious ocular adverse events. Conclusions: KDB combined with cataract extraction showed safety and efficacy for decreasing IOP and the number of hypotensive medications in Latino patients after one year follow-up. Intraocular pressure spikes were associated with a higher risk for failure.