Browsing by Autor "Mildred Ericka Kubatz La Madrid"

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Asymptomatic multiorgan cysticercosis. A case report from Bolivia
(2025) Mildred Ericka Kubatz La Madrid; Jennifer Collazo Cruz; Yamila Cruz Cruz; Jhossmar Cristians Auza-Santiváñez; Freddy Ednildon Bautista-Vanegas; Benito Aguirre-Cruz; Ingrid Neysa Cabezas-Soliz; Carmen Julia Salvatierra-Rocha
Introduction: Cysticercosis is an infectious disease caused by Taenia solium, endemic to Latin America, Asia, and Africa. It is acquired by consuming Taenia eggs in contaminated water and food, or undercooked pork. It generally causes mild or asymptomatic disease, except for neurocysticercosis, which can be severe and potentially fatal. Symptoms depend on the number of parasites, their location, and the host's immune response. Diagnosis is based on epidemiological data, clinical presentation, and imaging studies, primarily computed tomography. Objective: To use computed tomographic images to identify the degree of tissue damage caused by Taenia solium in an asymptomatic Bolivian adult. Clinical case: A 52-year-old Bolivian female patient from a rural area, with a wooden house, dirt floor, no sewage or drinking water, a housewife, who practices open defecation and raises pigs to support her household. She had a personal health history, but an inadequate diet. She was taken to the Roberto Galindo Hospital due to a traffic accident, where an emergency CT scan of the head and abdomen was performed due to direct trauma to those areas. The studies revealed calcifications in multiple organs, findings suggestive of massive cysticercosis. Conclusions: Cysticercosis is a parasitic disease transmitted fecal-orally, preventable but highly contagious from country to country due to social migration. It constitutes a serious health problem due to the biological, economic, and social damage it entails, making increased epidemiological surveillance essential.
Atypical rash, a diagnostic challenge in clinical practice: A Case Report from Bolivia
(2025) C. Roman; Jhossmar Cristians Auza-Santiváñez; Paola Nielsen Fuentes Luzcuber; L. Castedo; Mildred Ericka Kubatz La Madrid; Sara Milca Robles-Nina; Carmen Julia Salvatierra Rocha; Jorge Márquez-Molina
Hand-foot-and-mouth disease, commonly caused by Coxsackievirus A16, can manifest in atypical and severe forms associated with the CVA6 serotype, termed "eczema coxsackium," which may mimic serious pathologies. This report describes the case of a 10-year-old boy with a diffuse maculopapular rash, targetoid and bullous lesions, and systemic compromise, initially diagnosed as erythema multiforme major. The discussion focuses on the differential diagnostic challenge with eczema herpeticum, highlighting that despite the alarming clinical presentation, etiological confirmation via PCR for CVA6 was crucial to rule out other infections, discontinue unnecessary acyclovir, and focus treatment on supportive care, leading to a favorable outcome. In conclusion, eczema coxsackium due to CVA6 should be considered in severe vesiculobullous rashes, with PCR being essential for an accurate diagnosis and proper management, as its prognosis is generally benign.
Bilateral Subdural Empyema, secondary to odontogenic infectious process. Case Report
(2024) Edwin Cruz Choquetopa; Jhossmar Cristians Auza-Santiváñez; Mildred Ericka Kubatz La Madrid; Blas Apaza-Huanca; Yenifer Zelaya-Espinoza; Maribel Zambrana-Mejia; F Salazar; Osman Arteaga Iriarte
Introduction: Subdural empyema (ESD) is a collection of pus between the dura mater and arachnoid, and constitutes a medical emergency due to its rapid progression and high mortality rate. Although ENT infections are the main causes, odontogenic infections can also lead to ESD. Early diagnosis, intravenous antibiotic therapy and surgical intervention are essential to reduce mortality.Clinical case: A 32-year-old male patient presented with a month-long picture of swelling and pain on the left side of the face, recently aggravated by fever, headache, vomiting and generalised tonic-clonic convulsions. He had a history of alcoholism and recurrent dental infections. Imaging revealed a bilateral subdural empyema with left-sided predominance. Urgent antibiotic treatment was initiated, followed by bilateral craniotomy and drainage of purulent material. In addition, a brain abscess and a subgaleal haematoma were managed. Cultures identified Streptococcus viridans and coagulase-negative Staphylococcus, with good response to targeted therapy. The patient progressed favourably and was discharged in good condition.Conclusions: In regions like Bolivia, the prevalence of odontogenic infections due to cultural and economic factors increases the risk of severe complications such as SDE. A multidisciplinary approach, including early diagnosis, broad-spectrum antibiotics, and surgical intervention, is essential to improve outcomes and reduce mortality in these patients
Characterization of ophthalmological manifestations in patients recovered from COVID-19
(2025) Kirenia Sera Herrero; Dayami Pérez Gómez; L. Castedo; Jorge Márquez-Molina; Mildred Ericka Kubatz La Madrid; José Bernardo Antezana-Muñoz; Dilma Villca-Villca; Ingrid Neysa Cabezas-Soliz; Jhossmar Cristians Auza-Santiváñez
Introduction: Since the end of 2019, the world has been immersed in a health crisis caused by COVID-19, with millions of deaths globally. Ocular involvement is associated with respiratory symptoms and may be the first manifestation of the disease. Objective: To describe the short- and long-term ophthalmological manifestations in patients recovered from COVID-19. Methodological design: A descriptive, longitudinal and prospective study was carried out. The universe was composed of patients recovered from COVID-19, who were being followed up in the national convalescent care protocol at the Hermanos Ameijeiras Hospital, and were referred to the Ophthalmology clinic from February 2021 to June 2023. The sample consisted of 180 eyes of 90 patients, who met the selection criteria. Results: There was a predominance of the age group composed of women between 40 and 49 years, which represented 34% of the total. Most cases (65.5%) were evaluated less than 3 months after the initial diagnosis. 25.5% of patients presented at least one ocular disease, with conjunctivitis being the most frequent (26.5%), followed by dry eye (18.3%). Conclusions: In the evolutionary follow-up, a decrease in ocular diseases initially diagnosed as conjunctivitis was observed, however, others such as dry eye remained unchanged in their percentage of presentation and clinical manifestations. Patients evaluated with a shorter time of evolution of COVID-19 presented more severe ocular conditions
Current perspectives in the diagnosis and management of bacterial meningitis. Literature review and update
(2025) Jhossmar Cristians Auza-Santiváñez; Blas Apaza-Huanca; C. Roman; P. Ussetti Gil; José Bernardo Antezana-Muñoz; Freddy Ednildon Bautista-Vanegas; Jorge Márquez-Molina; Mildred Ericka Kubatz La Madrid; Eloy Paycho Anagua
Introduction: Bacterial meningitis is a serious and potentially fatal disease that has represented a significant challenge to medicine since its identification in the 19th century. Despite advances in antimicrobial treatment, it remains a major cause of morbidity and mortality worldwide. This review aims to update current perspectives on the diagnosis and management of bacterial meningitis, focusing on its pathogenesis, clinical manifestations, diagnostic methods, and therapeutic strategies. Methods: A search for information was carried out in the period August-December 2024 in the SciELO, LILACS, Scopus, PubMed-MedLine databases, the Google Scholar search engine, as well as in the ClinicalKeys services. For the recovery of information, an advanced search strategy was used and the terms “meningitis or bacterial meningitis” were used, as well as their translations into the English language. To combine the terms, Boolean operators were used, with search formulas according to the syntax requested by each database. Furthermore, in order to achieve a review based on the best possible evidence, only studies of the type case series, original articles or systematic reviews were selected. Results and discussion: Bacterial meningitis develops when pathogens overcome the host's defense mechanisms, colonizing mucous membranes, invading the bloodstream and penetrating the subarachnoid space. The main pathogens include Streptococcus pneumoniae, Neisseria meningitidis and Haemophilus influenzae. The most common clinical manifestations are fever, headache, stiff neck and altered mental status. Diagnosis is based on analysis of cerebrospinal fluid (CSF), which shows pleocytosis, increased protein and decreased glucose. Empirical treatment includes antibiotics such as cefotaxime, ceftriaxone and vancomycin, together with dexamethasone as adjuvant therapy to reduce inflammation. Conclusions: Bacterial meningitis is a serious infection of the central nervous system, a medical emergency whose mortality and sequelae can be reduced with timely diagnosis and treatment. The key is to start treatment immediately and without delay. Prevention is the cornerstone of its control. Only through multidisciplinary management, which could include an expert infectious disease specialist, an intensive care physician, a specialized nurse and adequate laboratory equipment, can the impact of this devastating disease be mitigated.
Endobronchial tumor, diagnosis and clinical and imaging evolution. A case report
(2025) Yamila Cruz Cruz; Mildred Ericka Kubatz La Madrid; Orlian Moreno Perera; Jennifer Collazo Cruz; Jhossmar Cristians Auza-Santiváñez; Benito Aguirre-Cruz; Yenifer Zelaya-Espinoza; Grobert Condori-Galindo
Introduction: Lung cancer has been known since the 19th century, and to date has experienced multiple advances in diagnosis and treatment, which imply a favorable prognosis for the patient. However, worldwide it exhibits high morbidity and mortality rates, it occurs mainly in males, with an average age of 65 years, is closely related to smoking and is notable for its low survival rates, particularly when diagnosed in advanced stages, as often occurs in endobronchial presentation. Objective: To describe the diagnosis and clinical imaging evolution of a patient with an endobronchial tumor. Case presentation: A 56-year-old male patient, a smoker and a carpenter by profession, who began to present chest pain and a dry, irritating cough and went to the family doctor. A series of complementary tests were prescribed, which yielded pathological results, including a chest X-ray, which supported the initial diagnosis, and a computed axial tomography (CT) scan, which confirmed the presence of an endobronchial tumor. Oncological staging and follow-up were performed, and despite complications that arose due to the patient's withdrawal from the consultation, the patient progressed well. Conclusions: Early diagnosis of lung cancer based on clinical methods and imaging studies is essential. This can improve survival and reduce the physical, emotional, and social impact on the patient and their family, as demonstrated in our clinical case. A multidisciplinary approach is essential, combining technology, clinical knowledge, and human sensitivity to provide comprehensive care and improve the patient's quality of life.
Measles: A Comprehensive Review of the Virus and Its Public Health Implications
(2025) C. Roman; Jhossmar Cristians Auza-Santiváñez; Cleotilde U. Torres; Freddy Ednildon Bautista-Vanegas; Daniel Ramiro Elías Vallejos-Rejas; Henrry Temis Quisbert-Vasquez; José Bernardo Antezana-Muñoz; Giovanni Callizaya Macedo; Mildred Ericka Kubatz La Madrid
Historically, measles has been an infectious disease responsible for significant morbidity and mortality worldwide. Global vaccination efforts have had a transformative impact, with measles immunization estimated to have prevented more than 60 million deaths globally between 2000 and 2023. Despite these successes, the global goal of measles elimination by 2030, outlined in the Measles and Rubella Strategic Framework 2021-2030, is now under considerable threat due to the recent re-emergence of the disease. Addressing the measles crisis is not only about containing this specific virus, but also about strengthening the fundamental resilience of public health systems worldwide to prepare for and mitigate a broader spectrum of infectious disease threats. This narrative review article aims to provide a comprehensive analysis of the global re-emergence of measles. Clinical and epidemiological trends will be detailed, key factors contributing to this resurgence will be identified, and public health implications will be examined. An analysis of the situation in Bolivia will be included, offering localized perspectives on the challenges and responses. Finally, the article will conclude with strategic recommendations for public health interventions and future preparedness.
Mountain sickness: physiological challenges, diagnosis and treatment
(2025) Jhossmar Cristians Auza-Santiváñez; P. Ussetti Gil; Mildred Ericka Kubatz La Madrid; Ingrid Neysa Cabezas-Soliz; Jorge Márquez-Molina; Yamila Cruz Cruz; Dilma Villca-Villca; R. Sarmiento
INTRODUCTION. The first descriptions of altitude sickness were made in (1540-1600). Nowadays, different cities in the world are at high altitude, for example Qinghai-Tibetan Plateau in China occupies an area of almost 2.5 million inhabitants km2, with an average elevation of over 4,500 m. Altitude sickness should be a major concern for anyone who normally resides at sea level. METHOD. A search for information was carried out in the period August-December 2024 in the SciELO, LILACS, Scopus, PubMed-MedLine databases, the Google Scholar search engine, as well as in the ClinicalKeys services. RESULTS AND DISCUSSION. The partial pressure of arterial oxygen (PaO2 ) decreases with altitude, which produces progressive tissue hypoxia. The normal compensatory response to hypobaric hypoxia is called acclimatization. Its main characteristic is increased ventilation. The ability to acclimatize varies widely among individuals and depends on many factors, including the degree of hypoxic stress (rate of ascent, altitude reached), the intrinsic ability of the individual to compensate for the decrease in PaO2, and extrinsic factors. Progressive ascent produces greater hypoxic stress, requiring greater degrees of physiological and behavioral adaptations to preserve function. The more rapid the ascent and the higher the altitude, the greater the stress. Below 1500 m, symptoms of high altitude illness are generally not manifest. From approximately 1500 to 2500 m, symptoms are generally mild, if experienced at all. From approximately 2500 m, mild to moderate symptoms become quite common among unacclimatized visitors after a rapid ascent. As a general rule, people who normally reside below 1500 m should avoid an abrupt ascent to altitudes above 2800 m for sleeping. Sedative-hypnotics should be avoided during acclimatization. Abstinence from alcohol is safest
Multiple and bilateral renoureteral malformations. Case report and literature review
(2025) Mildred Ericka Kubatz La Madrid; Yamila Cruz Cruz; Jennifer Collazo Cruz; Yamily Cruz Pino; Jhossmar Cristians Auza-Santiváñez; L. Castedo; Giovanni Callizaya Macedo; Roger Mamani Plata
Congenital malformations constitute anomalies of structure and/or function of prenatal origin, which are often asymptomatic or cause few symptoms, but currently have a high incidence. With the aim of showing the findings detected in the imaging studies carried out, the case of a young adult with repeated mild urinary sepsis is presented, who was diagnosed with multiple and bilateral renoureteral malformations in the infertility consultation. The majority of congenital renoureteral malformations imply serious biopsychosocial problems for the patient, with the consequent impact on the psychological sphere and the social life of family members when diagnosed in the prenatal stage, so they inevitably constitute a health problem, since they contribute to fetal and infant mortality or increased morbidity in any age group. For this reason, early diagnosis is essential to guarantee appropriate behavior and quality of life. Keywords: congenital malformations; renoureteral malformations; early diagnostic; ultrasound; descending urogram; double excretory system; ureterocele; reflux vesicoureteral
Neurological complications in patients with Human Immunodeficiency Virus infection at the Japanese Hospital in Santa Cruz, Bolivia
(2025) Carmen Julia Salvatierra-Rocha; Jhossmar Cristians Auza-Santiváñez; Alejandro Peralta Landívar; Carlos Lá Fuente Zerain; Mildred Ericka Kubatz La Madrid; Yamila Cruz Cruz; P. Ussetti Gil; Marco Antonio Gumucio Villarroel; Dulce María Hernández Vázquez
Introduction: Neurological involvement is common among patients with Human Immunodeficiency Virus (HIV) infection. Between 40 and 60% will develop symptomatic neurological complications with high morbidity and mortality at some point. Objective: To analyze the clinical-epidemiological characteristics of patients with HIV infection who develop neurological complications at the Japanese Hospital of Santa Cruz de la Sierra in the period between March 2019 and February 2022.Methods: Observational, descriptive, prospective, cross-sectional study. Universe and Sample: Patients admitted through the Emergency Service of the Japanese Hospital with a confirmed diagnosis of Human Immunodeficiency Virus Disease during the period between March 2019 and February 2022Results and discussion: A total of 42 patients were evaluated, the majority of whom were men and had a younger average age. For both sexes, the majority of patients reported having a source of employment. Regarding sexual orientation, almost all women reported being heterosexual, while men were more variable, with the majority being bisexual. Three clinical syndromes were identified at admission. The frequency of focal syndrome was dominant in women, but was not significantly different from the others. In men, meningeal syndrome and focal syndrome were the dominant ones, significantly exceeding non-focal syndrome. Ten neurological complications were identified, cerebral toxoplasmosis was the most frequent, followed by cerebral cryptococcosis and meningeal tuberculosis. Considering all patients in general, their typical hospital stay was 11 days with a range between 2 and 56 days. Of the 42 patients evaluated, it was only possible to measure the CD4 status for 27.Conclusions: The young male population with employment in the city of Santa Cruz with aberrant sexual behavior was the most affected. Focal syndrome was the most frequent form of presentation, in the form of cerebral toxoplasmosis. Severely low levels of immunosuppression were found in the study population. Hospital stay is variable and is longer in cases of focal syndrome and meningeal syndrome. We consider it important to continue the present study, which will allow us to increase the sample size.
Ramsay Hunt Syndrome in a Pediatric Patient with Atypical Presentation: Case Report
(2025) C. Roman; Paola Nielsen Fuentes Luzcuber; Jhossmar Cristians Auza-Santiváñez; Carmen Julia Salvatierra Rocha; Edson Grover Sañez Liendo; Henrry Temis Quisbert Vasquez; Mildred Ericka Kubatz La Madrid; Benito Aguirre-Cruz; Delly Espejo-Alanoca
The case of a preschooler with Ramsay Hunt Syndrome (RHS) is reported, an infrequent pediatric neurological condition caused by the reactivation of the varicella-zoster virus, whose atypical manifestation represented a diagnostic challenge. The patient, a 3-year and 4-month-old male, presented with vesicular lesions on the forehead and periorbital region, without the classic auricular rash, which led to a delayed diagnosis. Once RHS with bacterial superinfection was confirmed, acyclovir, prednisone, and antibiotics were administered, achieving a favorable evolution. The atypical presentation highlights the diagnostic challenges in children and the risk of delayed management. Therefore, it is crucial to maintain a high index of suspicion for RHS in pediatrics, even with unusual presentations, to ensure early treatment and prevent severe long-term complications.
Usefulness of ultrasound in the diagnosis of lumbricoid ascaris. Case Report and Literature Review
(2024) Ismael Vargas Gallego; Jhossmar Cristians Auza-Santiváñez; Ariel Sosa Remón; Eloy Paycho Anagua; Marco Antonio Gumucio Villarroel; R. Sarmiento; Mildred Ericka Kubatz La Madrid
Introduction. The World Health Organization (WHO) points out that more than a third of the world's population is infected by one or more parasites. Ascariasis is the most prevalent parasitic disease in the world, with approximately 664 million people infested. Clinical case. A 22-year-old female patient enters the emergency department with general malaise, with worsening symptoms in recent days, intense abdominal pain, associated with nausea and uncontrollable vomiting. She also reports non-elimination of gas and absence of bowel movements. . An emergency ultrasound is requested, it reports the stomach with the presence of a linear, tubular echogenic image that moves in different directions. Discussion. The widespread use of ultrasound in Emergency Departments for the diagnosis of acute abdomen, as well as in the laboratory, allowed us to reach the presumptive diagnosis of temporary biliary obstruction due to A. lumbricoides, in addition, the presence of jaundice, direct hyperbilirubinemia and discrete elevation gamma-glutamyltransferase (GGT); findings that could direct the exploration of the bile duct during the surgical procedure. Conclusions. The importance of the clinical case lies in the use of abdominal ultrasound as a diagnostic method for Ascaris Lumbricoides. The use of ultrasound in emergency services is essential in the presence of an acute abdomen, and in any patient who presents acute biliary symptoms, always think about this pathology