Efecto del calcio nixtamalizado en la recuperación del crecimiento en niños con malnutrición crónica dentro de un manejo integral
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Gac Med Bol
Abstract
Objetivos: valorar el efecto de calcio de maíz nixtamalizado sobre el crecimiento de niños con malnutrición crónica. Previa determinación de características fisicoquímicas, se elaboraron papillas para niños, 63 niños ingresaron al estudio. Métodos: estudio descriptivo controlado y seguimiento longitudinal, fueron incluidos 21 niños con retardo del crecimiento leve a moderado, quienes conformaron el grupo estudio (GE) y se beneficiaron de un esquema integral (clínica, laboratorio, antropometría, psicología, educación, nutrición). E grupo control fue también de 21 niños (GC) y recibió solo zinc como placebo. Ambos grupos fueron comparados con 21 niños sanos (GS) del mismo contexto social. Resultados: los niños del GE mejoraron ZT/E en promedio -1,1 ± 0,7 DS vs -2,5 ± 1,0 del GC (p<0,001) vs. GS 0,13 ± 0,14DS. La respuesta inmunitaria medida por ecografía del timo expresado en mm²fueen GE: 609,5 ± 123,6 DS vs. GC: 471,54 i 93,42DS (p<0,001) vs GS: 545,2 ± 0,8 DS. El desarrollo psicomotor en porcentaje: MF:GE: 97,8 ± 2,9 DS vs .GC: 90,9 ± 5,0 DS (p<0,01) vs.GS 99,5 ± 2,1 DE; MG: GE: 95,8 ± 2,9 vs GC: 80,6 ± 4,6 DS vs (p<0,01) GS: 97,6 ± 5,3DS; DLGE: 95,6 ± 4,1 vs. GC: 82,5 ± 4,8 DE (p<0,001) vs. GS 98,8 ± 5,4 DE; GPS: GE: 96,6 ± 4,8vs. GC: 80,6 ± 4,6 (p<0,001) vs. GS: 99,7 ± 1,0 DS. Asimismo el calcio iónico incrementó en GE: 5,1 ± 0,5 DE vs. GC: 4,1 ± 0,2 DE (p<0,001); GE: 25 hidroxi vitamina D se incrementó 52,5 ± 6,2 ng/ml. En el GE PTH llego a 21,5 ± 5,6 pg /mi y \¡ calcitonina ingresó dentro umbrales esperados 12,2 ± 1,5 pg /mi. Conclusiones: la recuperación del crecimiento de niños es mejor con calcio nixtamalizado dentro de un manejo integral.
Objective: to assesst effect of corn calcium nixtamalized about the growth of children with chronic malnutrition. Previous determinatiorj of physicochemical characteristics, were prepared porridge for children , 63 children enrolled to the study. Method: descriptive study controlled and longitudinal follow-up work, were included 21 children with slight to modérate delayed growth, who formed the studj group (GE ) and benefited from a comprehensive scheme (clinical, laboratory, anthropometry, psychology, education, nutrition ).Tha control group was also 21 children (GC) and they just received zinc received like placebo. Both groups were compared with 21 health) children (GS) in the same social context. Results: GE children improved ZT/Eon average-1.1 ±0.7 vs.-2.5 ± 1.0DSGC( p<0,001 ) vs.GS 0.13 ±0,14DS.Theimmuneresponsemeasured by ultrasound thymus was expressed in mm2 in the GE group: DSvs. 609.5 ± 123.6GC 471.54 ± 93,42DS ( p<0,001 ) vs GS: 545.2 ± 0.8 DS. Psychomotor development in percentage: MF : GE : 97.8 ± 2.9 vs DS .GC: 90.9 ± 5.0 DS ( p<0,01 ) vs.GS 99.5 ± 2.1 SD; MG : GE : GC 95.8 ± 2.9 vs 80.6 ± 4.6 vs DS ( p<0,01 ) GS: 97.6 ± 5,3DS ; DL : GE : 95.6 ± 4.1 vs. GC: 82.5 ± 4.Í DE ( p<0,001 ) vs. GS: 98.8 ± 5.4 SD; GPS : GE : 96.6 ± 4,8vs . GC: 80.6 ± 4.6 ( p<0,001 ) vs. GS: 99.7 ± 1.0 DS. Also calcium ion GE increasec 5.1 ± 0.5 SD vs. GC: 4.1 ± 0.2 (P < 0.001 ); GE : 25 hydroxy vitamin D was increased 52.5 ± 6.2 ng / mi. In the GE PTH carne to 21.5 ± 5.6 pe /mi and calcitonin entered within expected thresholds 12.2 ± 1.5 pg / mi. Conclusions: the recovery of growth in children is better with calcium nixtamalized within a integrated management.
Objective: to assesst effect of corn calcium nixtamalized about the growth of children with chronic malnutrition. Previous determinatiorj of physicochemical characteristics, were prepared porridge for children , 63 children enrolled to the study. Method: descriptive study controlled and longitudinal follow-up work, were included 21 children with slight to modérate delayed growth, who formed the studj group (GE ) and benefited from a comprehensive scheme (clinical, laboratory, anthropometry, psychology, education, nutrition ).Tha control group was also 21 children (GC) and they just received zinc received like placebo. Both groups were compared with 21 health) children (GS) in the same social context. Results: GE children improved ZT/Eon average-1.1 ±0.7 vs.-2.5 ± 1.0DSGC( p<0,001 ) vs.GS 0.13 ±0,14DS.Theimmuneresponsemeasured by ultrasound thymus was expressed in mm2 in the GE group: DSvs. 609.5 ± 123.6GC 471.54 ± 93,42DS ( p<0,001 ) vs GS: 545.2 ± 0.8 DS. Psychomotor development in percentage: MF : GE : 97.8 ± 2.9 vs DS .GC: 90.9 ± 5.0 DS ( p<0,01 ) vs.GS 99.5 ± 2.1 SD; MG : GE : GC 95.8 ± 2.9 vs 80.6 ± 4.6 vs DS ( p<0,01 ) GS: 97.6 ± 5,3DS ; DL : GE : 95.6 ± 4.1 vs. GC: 82.5 ± 4.Í DE ( p<0,001 ) vs. GS: 98.8 ± 5.4 SD; GPS : GE : 96.6 ± 4,8vs . GC: 80.6 ± 4.6 ( p<0,001 ) vs. GS: 99.7 ± 1.0 DS. Also calcium ion GE increasec 5.1 ± 0.5 SD vs. GC: 4.1 ± 0.2 (P < 0.001 ); GE : 25 hydroxy vitamin D was increased 52.5 ± 6.2 ng / mi. In the GE PTH carne to 21.5 ± 5.6 pe /mi and calcitonin entered within expected thresholds 12.2 ± 1.5 pg / mi. Conclusions: the recovery of growth in children is better with calcium nixtamalized within a integrated management.
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Vol. 38, No. 2