LIGNANS FROM IRYANTHERA JURUENSIS WARB

Abstract

Cuatro Lignanos Otobafenol (1), Cagayanin (2), Otobain (3) y Hydroxiotobain (4) se encontraron junto con un compuesto similar al tocoferol identificado como: (5S)-3a-acetil-2,3,5-trimetil7a-hidroxy-5-(4,8,12-trimethyltridecanil) 1,3a,5,6,7,7a-hexahydro-4-oxainden-1-ona (5) y un alcano lineal muy largo (6), reportado aquí como producto natural por primera vez, se encontraron en los extractos hexanicos y diclorometanicos de las hojas de Iryanthera Juruensis warb, usada frecuentemente como planta medicinal in la selva del amazonas, la elucidación estructural se realizo mediante espectroscopia de resonancia magnetica nuclear y espectrometria de masas.

Four lignans Otobaphenol (1), Cagayanin (2), Otobain (3) and Hydroxyotobain (4), together with a tocopherol like compound identified as (5S)-3a-acetyl-2,3,5-trimethyl-7a-hydroxy-5- (4,8,12-trimethyltridecanyl) -1,3a,5,6,7,7ahexahydro-4-oxainden-1-one (5) and a very long unbranched alcane (6) reported here as natural product for the first time were found in the hexane and dichloromethane extract from the leaves of Iryanthera Juruensis warb, a plant frequently used as a medicinal plant in the amazons rain forest, the structure elucidation was performed by NMR spectroscopy and mass spectrometry.