Chondroitin Sulfate-Degrading Enzymes as Tools for the Development of New Pharmaceuticals

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dc.contributor.authorRaúl Benito-Arenas
dc.contributor.authorSandra G. Zárate
dc.contributor.authorJulia Revuelta
dc.contributor.authorÁgatha Bastida
dc.coverage.spatialBolivia
dc.date.accessioned2026-03-22T14:13:44Z
dc.date.available2026-03-22T14:13:44Z
dc.date.issued2019
dc.descriptionCitaciones: 27
dc.description.abstractChondroitin sulfates are linear anionic sulfated polysaccharides found in biological tissues, mainly within the extracellular matrix, which are degraded and altered by specific lyases depending on specific time points. These polysaccharides have recently acquired relevance in the pharmaceutical industry due to their interesting therapeutic applications. As a consequence, chondroitin sulfate (CS) lyases have been widely investigated as tools for the development of new pharmaceuticals based on these polysaccharides. This review focuses on the major breakthrough represented by chondroitin sulfate-degrading enzymes and their structures and mechanisms of function in addition to their major applications.
dc.identifier.doi10.3390/catal9040322
dc.identifier.urihttps://doi.org/10.3390/catal9040322
dc.identifier.urihttps://andeanlibrary.org/handle/123456789/45288
dc.language.isoen
dc.publisherMultidisciplinary Digital Publishing Institute
dc.relation.ispartofCatalysts
dc.sourceInstituto de Química Orgánica General
dc.subjectChondroitin sulfate
dc.subjectChondroitin
dc.subjectPolysaccharide
dc.subjectChondroitin sulphate
dc.subjectChemistry
dc.subjectBiochemistry
dc.subjectEnzyme
dc.subjectFunction (biology)
dc.subjectSulfation
dc.titleChondroitin Sulfate-Degrading Enzymes as Tools for the Development of New Pharmaceuticals
dc.typearticle

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