Evaluation of a Competitive Antibody Enzyme Immunoassay for Specific Diagnosis of Chagas' Disease

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dc.contributor.authorWashington R. Cuna
dc.contributor.authorCarlos A. Rodríguez
dc.contributor.authorFaustino Torrico
dc.contributor.authorD. Afchain
dc.contributor.authorMarc Loyens
dc.contributor.authorP. Desjeux
dc.coverage.spatialBolivia
dc.date.accessioned2026-03-22T15:42:23Z
dc.date.available2026-03-22T15:42:23Z
dc.date.issued1989
dc.descriptionCitaciones: 8
dc.description.abstractA competitive enzyme immunoassay based on the use of a monoclonal antibody (MAb) specific for "component 5" of Trypanosoma cruzi was evaluated. The antigenicity and immunogenicity of this component has been observed in natural and experimental infections. The studies were conducted in an area of Bolivia where mixed infections with Leishmania braziliensis are frequent and present a problem in the accurate diagnosis of T. cruzi infections. The specificity and sensitivity of this assay as compared to the indirect immunofluorescence and ELISA tests were demonstrated. The present test has proved to be more specific than the immunofluorescence and ELISA tests.
dc.identifier.doi10.2307/3282588
dc.identifier.urihttps://doi.org/10.2307/3282588
dc.identifier.urihttps://andeanlibrary.org/handle/123456789/53932
dc.language.isoen
dc.publisherAmerican Society of Parasitologists
dc.relation.ispartofJournal of Parasitology
dc.sourceInstituto Boliviano de Ciencia y Tecnología Nuclear
dc.subjectImmunoassay
dc.subjectTrypanosoma cruzi
dc.subjectAntigenicity
dc.subjectBiology
dc.subjectImmunofluorescence
dc.subjectMonoclonal antibody
dc.subjectChagas disease
dc.subjectLeishmania braziliensis
dc.subjectImmunogenicity
dc.subjectLeishmaniasis
dc.titleEvaluation of a Competitive Antibody Enzyme Immunoassay for Specific Diagnosis of Chagas' Disease
dc.typearticle

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