Gliosarcoma: Un Tumor Cerebral Poco Común

Abstract

Gliosarcoma, a rare brain tumorAbstract The Gliosarcoma (GS) is an aggressive primary neoplasm and rare in central nervous system (CNS), composed of anaplastic astrocytic and mesenchymal elements clearly malignant. The clinical picture is characterized by headaches and seizures, presented as part of the initial symptoms in 30% of patients whose percentage increases as the disease progresses. Among the secondary manifestations, described changes as impaired concentration and personality of lesions particularly affecting the parietal lobe is associated with motor or sensory deficit. As for the MRI diagnosis, malignant gliomas are observed well-circumscribed with focal edema and capture the contrast in the periphery with a hypointense center. A case of male patient aged 45, whose clinical and imaging findings are consistent with those previously described by what is proposed the diagnosis of right parietooccipital glioma. When performing exeresis of the tumor histopathology was performed, which was reported as a glioblastoma multiform, and subsequent immunohistochemical analysis concluded definitively as a gliosarcoma. The low frequency of this pathological entity and the impact on morbidity and mortality of patients with the disease led to the filing of this case.