CHEMICAL EDUCATION: STRUCTURAL ELUCIDATION: PLICATIN A AND B FROM WERNERIA DACTYLOPHYLLA

Abstract

"Structural elucidation of natural products through spectrometric tools require practice to acquire ability enough for increasing the research production in tasks such as the quest of new natural origin or derived medical drugs or with chemosysematics or chemotaxonomic labors. Introducing the techniques to the newcomer would impose the presentation of problems in an explicit manner and with real examples. We present the detailed structural elucidation of plicatin B (1) known as methyl 3-(4-hydroxy-3-(3-methyl-2-butenyl)phenyl)-2-propenoate and we report the identification of plicatin A (2) known as methyl 4-hydroxy-3-(2-hydroxy-3-methyl-3-butenyl)-phenyl-trans-a-propenoate, two phenolic compounds reported here for the first time from the species Werneria dactylophylla. This paper includes an introduction with the bibliographic research and the description of the isolation and purification procedures, as well indeed a complete step-by-step structural elucidation proposal for 1. Also, an evaluation of the biological activities of the compounds is reported"