Antimalarial Activity and Cytotoxicity of (-)-Roemrefidine Isolated from the Stem Bark of<i>Sparattanthelium amazonum</i>

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dc.contributor.authorVerónica Francisca Loewe Muñoz
dc.contributor.authorMichel Sauvain
dc.contributor.authorPatricia Mollinedo
dc.contributor.authorJorgia Callapa
dc.contributor.authorI. Gina Rojas
dc.contributor.authorA. Giménez
dc.contributor.authorAlexis Valentin
dc.contributor.authorM. Mallié
dc.coverage.spatialBolivia
dc.date.accessioned2026-03-22T21:15:21Z
dc.date.available2026-03-22T21:15:21Z
dc.date.issued1999
dc.descriptionCitaciones: 42
dc.description.abstract(-)-Roemrefidine, an aporphine alkaloid isolated from Sparattanthelium amazonum Martius (Hernandiaceae) a vine from Bolivia, has been found to be active against both resistant and sensitive strains of Plasmodium falciparum in vitro and against P. berghei in mice. The compound demonstrated no cytotoxic activity against three cell lines (KB, HEp-2 and HeLa).
dc.identifier.doi10.1055/s-2006-960808
dc.identifier.urihttps://doi.org/10.1055/s-2006-960808
dc.identifier.urihttps://andeanlibrary.org/handle/123456789/86856
dc.language.isoen
dc.publisherThieme Medical Publishers (Germany)
dc.relation.ispartofPlanta Medica
dc.sourceInstituto Boliviano de Ciencia y Tecnología Nuclear
dc.subjectHeLa
dc.subjectPlasmodium falciparum
dc.subjectCytotoxicity
dc.subjectAnnonaceae
dc.subjectAlkaloid
dc.subjectAporphine
dc.subjectCytotoxic T cell
dc.subjectPharmacognosy
dc.subjectIn vitro
dc.subjectTraditional medicine
dc.titleAntimalarial Activity and Cytotoxicity of (-)-Roemrefidine Isolated from the Stem Bark of<i>Sparattanthelium amazonum</i>
dc.typeletter

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