Genetic Selection of Low Fertile Onchocerca volvulus by Ivermectin Treatment

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dc.contributor.authorCatherine Bourguinat
dc.contributor.authorSébastien D. S. Pion
dc.contributor.authorJoseph Kamgno
dc.contributor.authorJacques Gardon
dc.contributor.authorB. O. L. Duke
dc.contributor.authorMichel Boussinesq
dc.contributor.authorRoger K. Prichard
dc.coverage.spatialBolivia
dc.date.accessioned2026-03-22T14:01:54Z
dc.date.available2026-03-22T14:01:54Z
dc.date.issued2007
dc.descriptionCitaciones: 111
dc.description.abstractThe results indicate that ivermectin is causing genetic selection on O. volvulus. This genetic selection is associated with a lower reproductive rate in the female parasites. We hypothesize that this genetic selection indicates that a population of O. volvulus, which is more tolerant to ivermectin, is being selected. This selection could have implications for the development of ivermectin resistance in O. volvulus and for the ongoing onchocerciasis control programmes.
dc.identifier.doi10.1371/journal.pntd.0000072
dc.identifier.urihttps://doi.org/10.1371/journal.pntd.0000072
dc.identifier.urihttps://andeanlibrary.org/handle/123456789/44136
dc.language.isoen
dc.publisherPublic Library of Science
dc.relation.ispartofPLoS neglected tropical diseases
dc.sourceMcGill University
dc.subjectIvermectin
dc.subjectOnchocerca volvulus
dc.subjectOnchocerciasis
dc.subjectBiology
dc.subjectGenotype
dc.subjectGenetics
dc.subjectGene
dc.titleGenetic Selection of Low Fertile Onchocerca volvulus by Ivermectin Treatment
dc.typearticle

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