Genotipos del Virus del Papiloma Humano en citología alterada del cuello uterino
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Vive Rev. Salud
Abstract
En Ecuador el cáncer de cuello uterino se ubica en el segundo lugar y, está relacionada a una infección genital persistente por el virus del papiloma humano (VPH) de alto riesgo. Objetivo general: determinar la relación entre virus del papiloma humano de alto riesgo y las lesiones intraepiteliales del cuello uterino, en mujeres de 21 a 65 años en tres cantones de la provincia de El Oro, periodo 2019. Se trata de un estudio de tipo descriptivo relacional de corte transversal. Se realizó el estudio en 109 mujeres que cumplieron los criterios de inclusión. Para la relación de las variables se utilizó los estadísticos del Chi cuadrado (con valor de p < 0.05). Los resultados observados fueron que, el 77, 06% de las participantes estuvo en la edad ≥ 30 años; el 77,98% inicio su vida sexual antes de los 20 años y, la edad del parto en el 77,06% fue antes de los 25 años. La prevalencia de lesiones intraepiteliales del cuello uterino fue del 18,37%, de estas el 16,13% se debieron al virus papiloma humano de alto riesgo; sin embargo, esta relación no fue significativa (p > 0,05) y, la lesión más frecuente fue el de células escamosas atípicas de importancia no determinada. Se concluye que las lesiones intraepiteliales fueron más frecuentes que las reportadas en la literatura como general, y los genotipos 39, 16, 18 estuvieron presentes en las lesiones intraepiteliales de bajo grado del cuello uterino.
In Ecuador, cervical cancer is in second place and is related to persistent genital infection by high-risk human papillomavirus (HPV). General objective: to determine the relationship between high-risk human papillomavirus and cervical intraepithelial lesions in women aged 21 to 65 years in three cantons of the province of El Oro, period 2019. This is a descriptive relational cross-sectional study. The study was conducted in 109 women who met the inclusion criteria. Chi-square statistics (with p value < 0.05) were used for the relationship of the variables. The results observed were that 77.06% of the participants were aged ≥ 30 years; 77.98% began their sexual life before the age of 20 years and the age of delivery in 77.06% was before the age of 25 years. The prevalence of intraepithelial lesions of the cervix was 18.37%, of which 16.13% were due to high-risk human papillomavirus; however, this relationship was not significant (p > 0.05) and the most frequent lesion was atypical squamous cell of undetermined significance. It is concluded that intraepithelial lesions were more frequent than those reported in the literature in general, and genotypes 39, 16, 18 were present in low-grade intraepithelial lesions of the cervix.
In Ecuador, cervical cancer is in second place and is related to persistent genital infection by high-risk human papillomavirus (HPV). General objective: to determine the relationship between high-risk human papillomavirus and cervical intraepithelial lesions in women aged 21 to 65 years in three cantons of the province of El Oro, period 2019. This is a descriptive relational cross-sectional study. The study was conducted in 109 women who met the inclusion criteria. Chi-square statistics (with p value < 0.05) were used for the relationship of the variables. The results observed were that 77.06% of the participants were aged ≥ 30 years; 77.98% began their sexual life before the age of 20 years and the age of delivery in 77.06% was before the age of 25 years. The prevalence of intraepithelial lesions of the cervix was 18.37%, of which 16.13% were due to high-risk human papillomavirus; however, this relationship was not significant (p > 0.05) and the most frequent lesion was atypical squamous cell of undetermined significance. It is concluded that intraepithelial lesions were more frequent than those reported in the literature in general, and genotypes 39, 16, 18 were present in low-grade intraepithelial lesions of the cervix.
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Vol. 5, No. 14