Clinical Outcomes After Transcatheter Aortic Valve Replacement in Patients With Concomitant Mitral Regurgitation

Objectives To describe the clinical outcomes of patients with severe aortic valve stenosis (AS) and concomitant mitral regurgitation (MR) undergoing transcatheter aortic valve replacement (TAVR) Methods A propensity‐score matched analysis including 267 patients who underwent TAVR between 2009 and 2023. Information on pre‐, intra‐, and postoperative variables was collected. The main outcomes were survival and freedom from readmission for heart failure on long term follow‐up comparing the group with significant MR (sMR) (moderate–severe) vs. the control group. Results The prevalence of sMR was 22%. TAVR improved the severity of MR in 65% of the patients. There were no significant differences on the main early postoperative outcomes. sMR was not associated with a lower survival on long‐term follow‐up but readmission for heart failure was higher in this group. Conclusions MR is highly prevalent in patients undergoing TAVR. The procedure has a beneficial effect on the severity of concomitant MR. sMR was not associated with a higher mortality in long‐term follow‐up, patients with sMR experience a significant improvement in symptoms after TAVR although sMR was associated with higher heart failure readmissions.