Activation of the free fatty acid receptor GPR40 by (+)-curcuphenol and related synthetic compounds

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dc.contributor.authorValdivia, Ana C
dc.contributor.authorBoketof, Åke
dc.contributor.authorOlde, Björn
dc.contributor.authorOwman, Christer
dc.contributor.authorVilaseca, Antonio
dc.contributor.authorFuentes, Lenny
dc.contributor.authorSterner, Olov
dc.coverage.spatialBolivia
dc.date.accessioned2026-03-23T14:37:32Z
dc.date.available2026-03-23T14:37:32Z
dc.date.issued2009
dc.descriptionVol. 26, No. 2
dc.description.abstractThe bio-guided fractionation of an ethanol extract of Baccharis genistelloides (L) Baker, a plant that traditionally is used to treat diabetes, yielded (+)-curcuphenol (1) as agonist of GPR40, a cell surface receptor for free fatty acids. This paper describes the agonistic activity of 1 as well as of a series of semi-synthetic and synthetic analogueses
dc.description.abstractThe bio-guided fractionation of an ethanol extract of Baccharis genistelloides (L) Baker, a plant that traditionally is used to treat diabetes, yielded (+)-curcuphenol (1) as agonist of GPR40, a cell surface receptor for free fatty acids. This paper describes the agonistic activity of 1 as well as of a series of semi-synthetic and synthetic analoguesen
dc.identifier.urihttp://www.scielo.org.bo/scielo.php?script=sci_arttext&pid=S0250-54602009000200005&tlng=es
dc.identifier.urihttps://andeanlibrary.org/handle/123456789/87811
dc.language.isoes
dc.publisherRev. Bol. Quim
dc.relation.ispartofRev. Bol. Quim
dc.sourceSciELO Bolivia
dc.subjectGPR40
dc.subjectBaccharis genistelloides
dc.subject(+)-Curcuphenol
dc.subject(+)-Curcuphenol-methyl-ether
dc.subject(+)-Dihydrocurcuphenol
dc.subject1-Bisabolone
dc.subject1-Bisabolol
dc.subjectGlobulol
dc.subjectBacchopetiolone
dc.titleActivation of the free fatty acid receptor GPR40 by (+)-curcuphenol and related synthetic compounds
dc.title.alternativeActivation of the free fatty acid receptor GPR40 by (+)-curcuphenol and related synthetic compounds
dc.typeArtículo Científico Publicado

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