Isoenzyme characterization of Leishmania braziliensis braziliensis isolates obtained from Bolivian and Peruvian patients

Abstract

Abstract. Thirty-four Leishmania isolates obtained from Bolivian and Peruvian patients infected with mucocutaneous leishmaniasis were characterized_by isoenzyme electrophoresis using 10 enzymatic markers; all belonged to the-subspecies L. b. braziliensis. Three isolates showed marked variation compared with the reference-strain with respect to 5 or 6 enzymes. These variant isolates originated from patients with forms of the disease which were unresponsive to treatment.