Antiprotozoal Activity of Ethanol Extracts of Some<i>Bomarea</i>Species

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dc.contributor.authorFernando Álzate
dc.contributor.authorNora Jiménez
dc.contributor.authorBernard Weniger
dc.contributor.authorJaume Bastida
dc.contributor.authorAlberto Giménez
dc.coverage.spatialBolivia
dc.date.accessioned2026-03-22T15:12:04Z
dc.date.available2026-03-22T15:12:04Z
dc.date.issued2008
dc.descriptionCitaciones: 4
dc.description.abstractThe antiprotozoal activity of 26 ethanol extracts derived from 13 species of the genus Bomarea (Alstroemeriaceae) were evaluated against the promastigote forms of three Leishmania species (L. amazonensis L., L. braziliensis Vianna, and L. donovani Laveran & Mesnil) and the epimastigote form of Trypanosoma cruzi Chagas. IC50 values for leishmanicidal activities were between 4.9 and 98.6 μ g/mL, B. setacea extracts being the most active against the three species of Leishmania. Amphotericin B (IC50 = 0.2 μ g/mL) and pentamidine (IC50 = 10 μ g/mL) were used as control in this assay. IC50 values for antitrypanosomal activities were between 65.2 and 92.7 μ g/mL, whereas the control benznidazole had an IC50 value of 2 μ g/mL.
dc.identifier.doi10.1080/13880200801968904
dc.identifier.urihttps://doi.org/10.1080/13880200801968904
dc.identifier.urihttps://andeanlibrary.org/handle/123456789/50971
dc.language.isoen
dc.publisherTaylor & Francis
dc.relation.ispartofPharmaceutical Biology
dc.sourceUniversidad de Antioquia
dc.subjectAntiprotozoal
dc.subjectTrypanosoma cruzi
dc.subjectPentamidine
dc.subjectIC50
dc.subjectBenznidazole
dc.subjectLeishmania braziliensis
dc.subjectLeishmania
dc.subjectBiology
dc.subjectTraditional medicine
dc.subjectAmastigote
dc.titleAntiprotozoal Activity of Ethanol Extracts of Some<i>Bomarea</i>Species
dc.typearticle

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