Evolution of naturally occurring 5'non-coding region variants of Hepatitis C virus in human populations of the South American region

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dc.contributor.authorGonzalo Moratorio
dc.contributor.authorMariela Martínez
dc.contributor.authorMaría Fernanda Gutiérrez
dc.contributor.authorKatiuska González
dc.contributor.authorRodney Colina
dc.contributor.authorLuis Fernando López Tort
dc.contributor.authorLilia López
dc.contributor.authorRicardo Recarey
dc.contributor.authorAlejandro G. Schijman
dc.contributor.authorPilar Moreno
dc.coverage.spatialBolivia
dc.date.accessioned2026-03-22T15:02:20Z
dc.date.available2026-03-22T15:02:20Z
dc.date.issued2007
dc.descriptionCitaciones: 10
dc.description.abstractPhylogentic analysis revealed the presence of a sequence signature in the 5'NCR of type 1 HCV strains isolated in South America. This signature is frequent enough in type 1 HCV populations circulating South America to be detected in a phylogenetic tree analysis as a distinct type 1 sub-population. The coexistence of distinct type 1 HCV subpopulations is consistent with quasispecies dynamics, and suggests that multiple coexisting subpopulations may allow the virus to adapt to its human host populations.
dc.identifier.doi10.1186/1743-422x-4-79
dc.identifier.urihttps://doi.org/10.1186/1743-422x-4-79
dc.identifier.urihttps://andeanlibrary.org/handle/123456789/50019
dc.language.isoen
dc.publisherBioMed Central
dc.relation.ispartofVirology Journal
dc.sourceUniversidad de la República
dc.subjectPhylogenetic tree
dc.subjectBiology
dc.subjectLineage (genetic)
dc.subjectHepatitis C virus
dc.subjectVirology
dc.subjectPhylogenetics
dc.subjectGenetics
dc.subjectCoding region
dc.subjectEvolutionary biology
dc.subjectGenotype
dc.titleEvolution of naturally occurring 5'non-coding region variants of Hepatitis C virus in human populations of the South American region
dc.typearticle

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