Impact of benznidazole treatment on the functional response of Trypanosoma cruzi antigen-specific CD4+CD8+ T cells in chronic Chagas disease patients

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dc.contributor.authorElena Pérez-Antón
dc.contributor.authorAdriana Egui
dc.contributor.authorM. Carmen Thomas
dc.contributor.authorConcepción J. Puerta
dc.contributor.authorJohn Mario González
dc.contributor.authorAdriana Cuéllar
dc.contributor.authorManuel Segovia
dc.contributor.authorManuel Carlos López
dc.coverage.spatialBolivia
dc.date.accessioned2026-03-22T14:13:19Z
dc.date.available2026-03-22T14:13:19Z
dc.date.issued2018
dc.descriptionCitaciones: 28
dc.description.abstractCD4+CD8+ T cells could play an important role in the control of T. cruzi infection since they were able to produce effector molecules for parasite control. Benznidazole treatment partially reversed the exhaustion process caused by T. cruzi infection in these cells with an improvement in the functional response of the T. cruzi antigen-specific CD4+CD8+ T cells.
dc.identifier.doi10.1371/journal.pntd.0006480
dc.identifier.urihttps://doi.org/10.1371/journal.pntd.0006480
dc.identifier.urihttps://andeanlibrary.org/handle/123456789/45247
dc.language.isoen
dc.publisherPublic Library of Science
dc.relation.ispartofPLoS neglected tropical diseases
dc.sourceInstituto de Parasitología y Biomedicina "López - Neyra"
dc.subjectBenznidazole
dc.subjectTrypanosoma cruzi
dc.subjectChagas disease
dc.subjectImmunology
dc.subjectAntigen
dc.subjectCD8
dc.subjectVirology
dc.subjectBiology
dc.subjectDisease
dc.subjectMedicine
dc.titleImpact of benznidazole treatment on the functional response of Trypanosoma cruzi antigen-specific CD4+CD8+ T cells in chronic Chagas disease patients
dc.typearticle

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