Electrocardiographic alterations during treatment of mucocutaneous leishmaniasis with meglumine antimoniate and allopurinol

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dc.contributor.authorG Antezana
dc.contributor.authorR. Jorge Zeballos
dc.contributor.authorCristo A Carrasco Mendoza
dc.contributor.authorPhilippe Lyèvre
dc.contributor.authorL Valda
dc.contributor.authorFernando Cárdenas
dc.contributor.authorIrma Noriega
dc.contributor.authorHelena Ugarte
dc.contributor.authorJ. P. Dédet
dc.coverage.spatialBolivia
dc.date.accessioned2026-03-22T14:31:34Z
dc.date.available2026-03-22T14:31:34Z
dc.date.issued1992
dc.descriptionCitaciones: 37
dc.description.abstractThe electrocardiographic (ECG) changes in Bolivian patients with mucocutaneous leishmaniasis, treated with meglumine antimoniate and allopurinol, were evaluated. Electric changes due to the antimonial compound appeared in 45% of the patients, and consisted of repolarization alteration, principally affecting the T wave and the S-T segment. The changes disappeared within 2 months following the end of the antimonial treatment. In patients with associated Chagas disease and leishmaniasis, antimonial therapy did not aggravate the ECG changes characteristic of Chagasic cardiopathy.
dc.identifier.doi10.1016/0035-9203(92)90427-e
dc.identifier.urihttps://doi.org/10.1016/0035-9203(92)90427-e
dc.identifier.urihttps://andeanlibrary.org/handle/123456789/47023
dc.language.isoen
dc.publisherOxford University Press
dc.relation.ispartofTransactions of the Royal Society of Tropical Medicine and Hygiene
dc.sourceHigher University of San Andrés
dc.subjectMeglumine antimoniate
dc.subjectMedicine
dc.subjectLeishmaniasis
dc.subjectMucocutaneous zone
dc.subjectAllopurinol
dc.subjectInternal medicine
dc.subjectMeglumine
dc.subjectDermatology
dc.titleElectrocardiographic alterations during treatment of mucocutaneous leishmaniasis with meglumine antimoniate and allopurinol
dc.typearticle

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