Differences in Systemic and Skin Migrating-Specific CD4<sup>+</sup> T Cells in Papular Urticaria by Flea Bite

Abstract

Analysis of the cellular immune response against whole flea antigen in patients with papular urticaria by flea bites suggests a possible participation of inflammatory cytokines in the skin reaction (Th17) and a systemic control mechanism (IL-10). This pattern of cytokine production in patients could be a consequence of an impaired dendritic cell population.

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