Hypoglycemia and the Origin of Hypoxia-Induced Reduction in Human Fetal Growth

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dc.contributor.authorStacy Zamudio
dc.contributor.authorTatiana Torricos
dc.contributor.authorEwa Fik
dc.contributor.authorMaria Oyala
dc.contributor.authorLourdes Echalar
dc.contributor.authorJanet Pullockaran
dc.contributor.authorEmily Tutino
dc.contributor.authorBrittney Martin
dc.contributor.authorSonia Belliappa
dc.contributor.authorElfride Balanza
dc.coverage.spatialBolivia
dc.date.accessioned2026-03-22T13:52:53Z
dc.date.available2026-03-22T13:52:53Z
dc.date.issued2009
dc.descriptionCitaciones: 139
dc.description.abstractOur results support that preferential anaerobic consumption of glucose by the placenta at high altitude spares oxygen for fetal use, but limits glucose availability for fetal growth. Thus reduced fetal growth at high altitude is associated with fetal hypoglycemia, hypoinsulinemia and a trend towards lactacidemia. Our data support that placentally-mediated reduction in glucose transport is an initiating factor for reduced fetal growth under conditions of chronic hypoxemia.
dc.identifier.doi10.1371/journal.pone.0008551
dc.identifier.urihttps://doi.org/10.1371/journal.pone.0008551
dc.identifier.urihttps://andeanlibrary.org/handle/123456789/43264
dc.language.isoen
dc.publisherPublic Library of Science
dc.relation.ispartofPLoS ONE
dc.sourceHigher University of San Andrés
dc.subjectFetus
dc.subjectInternal medicine
dc.subjectEndocrinology
dc.subjectPregnancy
dc.subjectGlucose transporter
dc.subjectPlacenta
dc.subjectIntrauterine growth restriction
dc.subjectPlacental insufficiency
dc.subjectGlucose uptake
dc.subjectHypoxia (environmental)
dc.titleHypoglycemia and the Origin of Hypoxia-Induced Reduction in Human Fetal Growth
dc.typearticle

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