Eficacia y seguridad terapeutica del apafill-g™ en reparacion osea periapical mediante la vía endodontica

Abstract

Apical bone lesions in the tooth are mainly caused by pulpal disease. The restoration of these lesions goes from the radicular pulp treatment with calcium hydroxide until surgery. The aim of this study was to evaluate the mentioned medication combined with hydroxyapatite. Eight patients with periapical osteolytic lesions that consent to participate in the study, aged between 18 and 60 years, were treated. The treatment was carry out in two groups; the first one using calcium hydroxide and the second one with a mixture of equal parts of calcium hydroxide and hydroxyapatite (Apafill-G), both products were mixed with sterile distilled water. The evaluated variables were: clinical appearance of soft tissues and permanency of the filler for periods of 7, 15 y 30 days 3,6,8,9 y 12 months, measure by X Rays radiographs. The final evaluation assessed bone repair and adverse reactions in the categories of Success and Failure. The results showed a radiographic permanency of the calcium hydroxide filler of 44 %, while the combined treatment (calcium hydroxide mixed with hydroxyapatite) remained in the root canal in 90 % of applications. The clinical appearance in the initial evaluation had one Bad case in group 2, which was evaluated as Well when repeating the instrumentation and filling, showing apical repair and absence of adverse reactions. Can be concluded that apical repair was achieved for both treatments and that the intracanal filler combined with hydroxyapatite achieved a significantly higher permanence of the filler, without adverse reactions.