[ Active trypanocidal alkaloids, bisbenzylisoquinoles ii. active in vitro against trypanosoma cruzi the agent responsible for trypanosomiasis, south america].

Simple item page
dc.contributor.authorFournet, A
dc.contributor.authorManjon, A M
dc.contributor.authorMuñoz, V
dc.contributor.authorAngelo, A
dc.contributor.authorBruneton, J
dc.contributor.authorHocquemiller, R
dc.contributor.authorCortes, D
dc.contributor.authorCavé, A
dc.coverage.spatialBolivia
dc.date.accessioned2026-03-24T15:08:45Z
dc.date.available2026-03-24T15:08:45Z
dc.date.issued1988
dc.descriptionVol. 24, No. 2-3, pp. 337-43
dc.description.abstractChagas disease caused by the protozoan Trypanosoma cruzi is an endemic parasitic disease in Central and South America. The chemotherapeutic agents against Trypanosoma cruzi (imidazol compounds, lampit and benznidazol) are not very convenient products. Since it is known that protozoan Trypanosoma are close to Leishmania we studied the action of 14 bisbenzylisoquinoline alkaloids, in vitro, on three strains of T. cruzi (Tulahuen, C8C11, and 1979 CL1). As in the case of Leishmania, gyrocarpine, daphnandrine and obaberine showed an interesting activity and we judge them to be worthy of in vivo assays.fre
dc.description.sponsorshipLaboratoire de Pharmacognosie, ORSTOM-IBBA, La Paz, Bolivia.
dc.identifier.doi10.1016/0378-8741(88)90163-8
dc.identifier.issn0378-8741
dc.identifier.otherPMID:3075676
dc.identifier.urihttps://doi.org/10.1016/0378-8741(88)90163-8
dc.identifier.urihttps://andeanlibrary.org/handle/123456789/101465
dc.language.isofre
dc.relation.ispartofJournal of ethnopharmacology
dc.sourcePubMed
dc.title[ Active trypanocidal alkaloids, bisbenzylisoquinoles ii. active in vitro against trypanosoma cruzi the agent responsible for trypanosomiasis, south america].
dc.typeArtículo Científico Publicado

Files

Collections

Artículo Científico Publicado