¿Cuánta masa grasa y masa libre de grasa tienen los escolares de gran altitud? Datos de escolares usando la metodología de isotopos estables: indices de masa grasa y masa libre de grasa
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Cuad. - Hosp. Clín.
Abstract
El estudio de la vida a gran altitud es apasionante, sus antecedentes de una civilización antigua demuestran el gran desarrollo que existía en diferentes niveles del conocimiento. La fisiología de habitantes de gran altitud presenta diferencias descritas en tratados de enseñanza, más no así descripciones y análisis como se puede lograr al estudiar en profundidad características propias de funcionamiento en condiciones naturales de hipoxia hipobárica. La ciencia nuclear, aplicada en estudios de gran altitud, utiliza un principio fisiológico-biofísico muy importante como la dilución isotópica (caso del deuterio, isótopo estable, no radiactivo) para evaluar el agua corporal total, y a partir de ello determinar la masa libre de grasa y la masa grasa. La obesidad, como exceso de grasa corporal, no puede ser detectada por el índice de masa corporal (IMC), ya que tiene baja sensibilidad para hacerlo en la infancia. Valores similares de IMC en escolares de gran altitud pueden contener diferentes valores de índice de masa grasa (IMG) e índice de masa libre de grasa (IMLG). La interpretación de la significancia clínica de los índices de masa grasa y masa libre de grasa, en términos de normalización de kg para la talla en escolares, es de suma importancia para la evaluación pediátrica en salud y nutrición y la predicción futura de enfermedades crónicas no transmisibles en un contexto de gran altitud.
The study of life at high altitude is exciting, its antecedents of an ancient civilization demonstrate the great development that existed at different levels of knowledge. The physiology of high-altitude inhabitants presents differences described in teaching treatises, but not descriptions and analysis as can be achieved by studying in depth characteristics of functioning in natural conditions of hypobaric hypoxia. Nuclear science, applied in high altitude studies, uses a very important physiological- biophysical principle such as isotopic dilution (in the case of deuterium, a stable, non-radioactive isotope) to evaluate total body water, and from this determine the free mass of fat and fat mass. Obesity, as excess body fat, cannot be detected by the body mass index (BMI), since it has low sensitivity to do so in childhood. Similar BMI values in high-altitude schoolchildren may contain different values of fat mass index (FMI) and fat-free mass index (FMI). The interpretation of the clinical significance of the fat mass and fat-free mass indices, in terms of normalization of kg for height in schoolchildren, is of utmost importance for pediatric health and nutrition evaluation and the future prediction of chronic diseases. transmissible in a high altitude context.
The study of life at high altitude is exciting, its antecedents of an ancient civilization demonstrate the great development that existed at different levels of knowledge. The physiology of high-altitude inhabitants presents differences described in teaching treatises, but not descriptions and analysis as can be achieved by studying in depth characteristics of functioning in natural conditions of hypobaric hypoxia. Nuclear science, applied in high altitude studies, uses a very important physiological- biophysical principle such as isotopic dilution (in the case of deuterium, a stable, non-radioactive isotope) to evaluate total body water, and from this determine the free mass of fat and fat mass. Obesity, as excess body fat, cannot be detected by the body mass index (BMI), since it has low sensitivity to do so in childhood. Similar BMI values in high-altitude schoolchildren may contain different values of fat mass index (FMI) and fat-free mass index (FMI). The interpretation of the clinical significance of the fat mass and fat-free mass indices, in terms of normalization of kg for height in schoolchildren, is of utmost importance for pediatric health and nutrition evaluation and the future prediction of chronic diseases. transmissible in a high altitude context.
Description
Vol. 65, No. 2