Calcined Mg-Al hydrotalcites catalyst in the regioselective synthesis of silylated vicinal azidohydrins

Abstract

Calcined Mg-Al Hydrotalcites x = 0.20, 0.27, 0.33 proved effective catalysts for the oxirane ring opening reaction with trimethylsilyl azide in n-heptane at room temperature, yielding quantitative silylated vicinal azidohydrins. The catalyst was reused in several cycles presenting a consistent activity.