Impact of standardized immunophenotyping and MRD monitoring on early mortality reduction in childhood leukemia: a step towards addressing healthcare disparities in vulnerable populations from Southern Mexico

Abstract

Centralized, standardized MRD monitoring at the CCCL was associated with a reduction in early mortality and improved one-year survival in children with B-ALL from a socioeconomically vulnerable population. These findings demonstrate the clinical value and feasibility of implementing MRD-informed response assessment in LMICs and highlight the potential of centralized diagnostic platforms to reduce survival disparities in childhood leukemia.