Efecto epitelizante y analgésico del sevoflurano tópico en el tratamiento de las úlceras por presión grado I-III no infectadas Hospital Obrero N°1 de La Paz Bolivia
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Cuad. - Hosp. Clín.
Abstract
INTRODUCCIÓN: Las úlceras por presión constituyen un importante problema de salud por su frecuencia, carácter crónico, costes económicos y una merma en la calidad de vida en pacientes internados en las unidades de cuidados especiales. MATERIAL Y MÉTODOS: El objetivo del estudio fue evaluar el efecto epitelizante y analgésico del sevoflurano aplicado tópicamente en úlceras por presión grado l-lll no infectadas de pacientes internados. El tipo de estudio fue Ensayo clínico aleatorizado. Un total de 16 pacientes fueron incluidos en el estudio y fueron divididos aleatoriamente en 2 grupos: grupo A (8 pacientes), en los que se realizó la curación con sevoflurano tópico más povidona yodada y, grupo B (8 pacientes) curación solo con yodopovidona. La valoración de la evolución de la úlcera se realizó mediante la Escala PUSH, que valora superficie, cantidad de exudado y tipo de tejido del lecho. RESULTADOS: Durante la realización de la curación, el dolor manifestado por los integrantes del Grupo A (1.6 ± 0.7), fue mucho menor que el observado el Grupo B (7.2 ± 1). No se encontró diferencias significativas en la superficie de la úlcera y en la cantidad de exudado; si se encontró una diferencia significativa en el tipo de tejido existente en el lecho ulceroso, en los pacientes del Grupo A se evidenció la presencia de tejido de granulación y epitelial a partir de la tercera semana de tratamiento, lo cual, en los pacientes del Grupo B, se observó a partir de la cuarta semana.
INTRODUCTION: Pressure ulcers constitute an important health problem due to their frequency, chronic nature, economic costs and a reduction in the quality of Ufe in patients hospitalized in special care units. MATERIAL AND METHODS: The aim of the study was to evalúate the epithelializing and analgesic effect of sevoflurane applied topically in uninfected grade l-lll pressure ulcers of hospitalized patients. The type of study was Randomized Clinical Tríal. A total of 16 patients were included in the study and were randomly divided into 2 groups: group A (8 patients), in which the cure was performed with topical sevoflurane plus povidone iodine, and group B (8 patients) only with povidone iodine. The evaluation of the evolution of the ulcer was performed using the PUSH Scale, which assesses suríace área, amount of exúdate and type ofbed tissue. RESULTS: During the healing, the pain manifested by the members of Group A (1.6 ± 0.7), was much lower than that observed in Group B (7.2 ± 1). No significant differences were found on the suríace of the ulcer and in the amount of exúdate; Ifa significant difference was found in the type o f tissue existing in the ulcer bed, in Group A patients the presence of epithelial and granulation tissue was evidenced starting the third week of treatment, which, in Group A patients B, was observed staríing the fouríh week.
INTRODUCTION: Pressure ulcers constitute an important health problem due to their frequency, chronic nature, economic costs and a reduction in the quality of Ufe in patients hospitalized in special care units. MATERIAL AND METHODS: The aim of the study was to evalúate the epithelializing and analgesic effect of sevoflurane applied topically in uninfected grade l-lll pressure ulcers of hospitalized patients. The type of study was Randomized Clinical Tríal. A total of 16 patients were included in the study and were randomly divided into 2 groups: group A (8 patients), in which the cure was performed with topical sevoflurane plus povidone iodine, and group B (8 patients) only with povidone iodine. The evaluation of the evolution of the ulcer was performed using the PUSH Scale, which assesses suríace área, amount of exúdate and type ofbed tissue. RESULTS: During the healing, the pain manifested by the members of Group A (1.6 ± 0.7), was much lower than that observed in Group B (7.2 ± 1). No significant differences were found on the suríace of the ulcer and in the amount of exúdate; Ifa significant difference was found in the type o f tissue existing in the ulcer bed, in Group A patients the presence of epithelial and granulation tissue was evidenced starting the third week of treatment, which, in Group A patients B, was observed staríing the fouríh week.
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Vol. 62, No. 1