Acción antifúngica in vitro del extracto de laurel "Laurus nobilis" frente a la Candida albicans
Date
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Publisher
Vive Rev. Salud
Abstract
Las infecciones causadas por Candida albicans tienen una incidencia recurrente a nivel global, producto al uso de antifúngicos, por ello, muchas investigaciones han buscado alternativas factibles a base de plantas medicinales. Objetivo Evaluar el efecto antifúngico in vitro del extracto de laurel "Laurus nobilis" frente a Candida albicans. Materiales y métodos Se realizó un estudio experimental, cuantitativo, cuya clasificación pertenece a un experimento puro, con un muestreo no probabilístico por conveniencia, a partir de una población de estudio comprendida por cepas comerciales de Candida albicans ATCC 10231 y el extracto de Laurus nobilis. Se evalúa la inhibición del crecimiento de la cepa ATCC 10231 en diluciones de 100%, 75%, 50% 25% y 10% del extracto de Laurus nobilis con dimetilsulfóxido (DMSO) Los resultados revelaron que el extracto de Laurus nobilis a concentraciones de 100, 75 y 50% presenta una acción antifúngica frente a Candida albicans. Este hecho se debe a la presencia de halos de inhibición, los cuales según la escala de Duraffourd, se catalogan como sensibles. Se concluye que los resultados obtenidos de los halos de inhibición en las diferentes concentraciones del extracto de laurel, en las cuales se puede afirmar que, el mismo, si posee un efecto antifúngico frente a Candida albicans.
Infections caused by Candida albicans have a recurrent incidence globally, due to the use of antifungals, therefore, many investigations have sought feasible alternatives based on medicinal plants. Objective To evaluate the in vitro antifungal effect of laurel extract "Laurus nobilis" against Candida albicans. Materials and methods An experimental, quantitative study was carried out, whose classification belongs to a pure experiment, with a non-probabilistic sampling by convenience, from a study population comprised of commercial strains of Candida albicans ATCC 10231 and the extract of Laurus nobilis. The inhibition of the growth of strain ATCC 10231 in dilutions of 100%, 75%, 50% 25% and 10% of Laurus nobilis extract with dimethyl sulfoxide (DMSO) was evaluated. The results revealed that Laurus nobilis extract at concentrations of 100, 75 and 50% presented an antifungal action against Candida albicans. This fact is due to the presence of inhibition halos, which according to the Duraffourd scale, are classified as sensitive. It is concluded that the results obtained from the inhibition halos in the different concentrations of the laurel extract, in which it can be affirmed that it does have an antifungal effect against Candida albicans.
Infections caused by Candida albicans have a recurrent incidence globally, due to the use of antifungals, therefore, many investigations have sought feasible alternatives based on medicinal plants. Objective To evaluate the in vitro antifungal effect of laurel extract "Laurus nobilis" against Candida albicans. Materials and methods An experimental, quantitative study was carried out, whose classification belongs to a pure experiment, with a non-probabilistic sampling by convenience, from a study population comprised of commercial strains of Candida albicans ATCC 10231 and the extract of Laurus nobilis. The inhibition of the growth of strain ATCC 10231 in dilutions of 100%, 75%, 50% 25% and 10% of Laurus nobilis extract with dimethyl sulfoxide (DMSO) was evaluated. The results revealed that Laurus nobilis extract at concentrations of 100, 75 and 50% presented an antifungal action against Candida albicans. This fact is due to the presence of inhibition halos, which according to the Duraffourd scale, are classified as sensitive. It is concluded that the results obtained from the inhibition halos in the different concentrations of the laurel extract, in which it can be affirmed that it does have an antifungal effect against Candida albicans.
Description
Vol. 8, No. 23
Keywords
Actividad antifúngica, Candida albicans, Extracto alcohólico, Halos de inhibición, Plantas medicinales, Principios bioactivos, Antifungal activity, Candida albicans, Alcoholic extract, Inhibition halos, Medicinal plants, Bioactive principles, Atividade antifúngica, Candida albicans, Extrato alcoólico, Auréolas de inibição, Plantas medicinais, Princípios bioactivos, Princípios bioactivos