HIGH SUSCEPTIBILITY OF CANDIDA ALBICANS ATCC 10231 TO TETRAHYDROFURANOSYL-1,2,3-TRIAZOLES OBTAINED BY CLICK CHEMISTRY
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Rev. Bol. Quim
Abstract
Tetrahydrofuranosyl-1,2,3-triazoles, synthesized by "Click chemistry", were tested as novel antifungal compounds. The results show a remarkable activity against Candida albicans ATCC 10231 expressed in a high MIC50 and MIC90 compared to traditional antifungals such as fluconazole.
Tetrahydrofuranosyl-1,2,3-triazoles, synthesized by "Click chemistry", were tested as novel antifungal compounds. The results show a remarkable activity against Candida albicans ATCC 10231 expressed in a high MIC50 and MIC90 compared to traditional antifungals such as fluconazole.
Tetrahydrofuranosyl-1,2,3-triazoles, synthesized by "Click chemistry", were tested as novel antifungal compounds. The results show a remarkable activity against Candida albicans ATCC 10231 expressed in a high MIC50 and MIC90 compared to traditional antifungals such as fluconazole.
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Vol. 31, No. 1