Métodos diagnósticos de laboratório para coronavirus 2019 n-cov
Date
Journal Title
Journal ISSN
Volume Title
Publisher
Vive Rev. Salud
Abstract
La Diabetes mellitus constituye uno de los problemas de salud más importantes en el mundo por la alta carga de enfermedad en términos de discapacidad y mortalidad prematura que ocasiona, debido a su alta prevalencia e incidencia a nivel mundial se configura como una epidemia. Objetivo . Determinar el riesgo para desarrollar diabetes mellitus tipo II en las personas de la Cuidad de Cuenca. Materiales y métodos . Se realizó un estudio, descriptivo, correlacional, prospectivo, cuantitativo y de corte transversal, mediante la aplicación del test de FINDRISC, La muestra estuvo compuesta por 379 personas no diabéticas con edades comprendidas entre 18 y 65 años de edad. Resultados . Se determinó que las variables sexo, edad, el peso, la talla, el perímetro de cintura, el tiempo diario de actividad física y antecedentes familiares de DM1- 2 presentan una correlación significativa en el nivel 0,01 (bilateral) con el riesgo de desarrollar DM2 según la puntuación del test de FINDRISC. Conclusión . Los datos obtenidos sugieren la necesidad de programas de intervención multidisciplinar en las unidades de salud asociados a programas educativos, ingesta dietética adecuada y actividad física regular.
Introduction . The multiple and unknown characteristics of coronavirus 2019-nCoV causing acute respiratory syndrome and millions of deaths worldwide prompted the rapid development of laboratory diagnostic techniques and kits based on the amplification of viral sequences or the determination of antibodies in blood, however, after their application disagreements were generated between the result with the true positivity or negativity of the disease. Objective . The following review seeks to characterize and evaluate the use of molecular and serological techniques, according to factors such as sensitivity and specificity, type of specimen and detection target. Methodology . The Scopus and Web of Since databases were used, obtaining 136 articles of which 25 met the inclusion criteria such as development, clinical validation and standardization of the technique, as well as new proposed methodologies. Results . 17 items correspond to the diagnosis of SARS-CoV-2 by molecular techniques and 8 by serological techniques. The greatest number of publications found came from China (5) and the United States (4), European countries (8) and Asia (6) while, in Latin America, publications were found from Brazil (1) and Ecuador (1). Conclusions . In relation to the above, molecular assays stand out for their high sensitivity and specificity and are used at any stage of the disease. Serological tests are recommended as a complement to molecular tests as well as for disease monitoring instead of being the only diagnostic marker.
Introduction . The multiple and unknown characteristics of coronavirus 2019-nCoV causing acute respiratory syndrome and millions of deaths worldwide prompted the rapid development of laboratory diagnostic techniques and kits based on the amplification of viral sequences or the determination of antibodies in blood, however, after their application disagreements were generated between the result with the true positivity or negativity of the disease. Objective . The following review seeks to characterize and evaluate the use of molecular and serological techniques, according to factors such as sensitivity and specificity, type of specimen and detection target. Methodology . The Scopus and Web of Since databases were used, obtaining 136 articles of which 25 met the inclusion criteria such as development, clinical validation and standardization of the technique, as well as new proposed methodologies. Results . 17 items correspond to the diagnosis of SARS-CoV-2 by molecular techniques and 8 by serological techniques. The greatest number of publications found came from China (5) and the United States (4), European countries (8) and Asia (6) while, in Latin America, publications were found from Brazil (1) and Ecuador (1). Conclusions . In relation to the above, molecular assays stand out for their high sensitivity and specificity and are used at any stage of the disease. Serological tests are recommended as a complement to molecular tests as well as for disease monitoring instead of being the only diagnostic marker.
Description
Vol. 4, No. 10