An open CAR-T single-cell atlas to enable in-depth characterization and rational engineering of CAR-T products

This record contains the datasets used in the manuscript to ensure full reproducibility of the results. Code and analysis workflows are available at: https://github.com/ML4BM-Lab/Functional-cart-atlas Pretrained atlas model is broadly available to the community through scVI-hub: https://huggingface.co/sergiocamarap/Functional-cart-atlas-model The atlas can be explored through an interactive Shiny application at: https://wholebioinfo.shinyapps.io/shinyatlas/ The atlas is also accessible through the UCSC Cell Browser at: https://car-t-atlas.cells.ucsc.edu Together, these resources provide an integrated framework to explore, validate, and extend the CAR-T cell atlas presented in the study.